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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IRS2 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0002053positive regulation of mesenchymal cell proliferationIEA
GO:0002903negative regulation of B cell apoptosisISS
GO:0006006glucose metabolic processTAS
GO:0007165signal transductionTAS
GO:0007420brain developmentIEA
GO:0008284positive regulation of cell proliferationNAS
GO:0008286insulin receptor signaling pathwayISS
GO:0008286insulin receptor signaling pathwayTAS
GO:0008543fibroblast growth factor receptor signaling pathwayTAS
GO:0009749response to glucose stimulusISS
GO:0010748negative regulation of plasma membrane long-chain fatty acid transportIMP
GO:0010907positive regulation of glucose metabolic processIMP
GO:0019216regulation of lipid metabolic processTAS
GO:0030335positive regulation of cell migrationIEA
GO:0030879mammary gland developmentIEA
GO:0030890positive regulation of B cell proliferationISS
GO:0032000positive regulation of fatty acid beta-oxidationIMP
GO:0032024positive regulation of insulin secretionISS
GO:0032869cellular response to insulin stimulusIMP
GO:0033673negative regulation of kinase activityISS
GO:0045725positive regulation of glycogen biosynthetic processIMP
GO:0045725positive regulation of glycogen biosynthetic processNAS
GO:0046326positive regulation of glucose importIMP
GO:0048011nerve growth factor receptor signaling pathwayTAS
GO:0048015phosphatidylinositol-mediated signalingTAS
GO:0055088lipid homeostasisTAS
cellular_component
GO:0005737cytoplasmIEA
GO:0005792microsomeIEA
GO:0005829cytosolTAS
GO:0005886plasma membraneTAS
molecular_function
GO:0004871signal transducer activityIEA
GO:0005158insulin receptor bindingIEA
GO:0019901protein kinase bindingIEA
GO:0043548phosphatidylinositol 3-kinase bindingIEA
GO:0046934phosphatidylinositol-4,5-bisphosphate 3-kinase activityTAS

Protein-protein interaction details for IRS2 (Homo sapiens)
(Information is obtained from BioGRID)
Not available