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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IRS2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8660
Official gene symbolIRS2
Full nameinsulin receptor substrate 2
Aliases,IRS-2,
Gene summaryThis gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq]
LocationChromosome: 13   Locus: 13q34
Gene position110438914 - 110406184  Map Viewer
Gene orientationminus
Gene size32731 bp
Gene sequence
OMIM ID600797