Database of mammalian genes
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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for INS (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000165
MAPKKK cascade
IDA
GO:0002674
negative regulation of acute inflammatory response
IDA
GO:0005975
carbohydrate metabolic process
IEA
GO:0006006
glucose metabolic process
IEA
GO:0006112
energy reserve metabolic process
TAS
GO:0006355
regulation of transcription, DNA-dependent
NAS
GO:0006521
regulation of cellular amino acid metabolic process
IMP
GO:0006953
acute-phase response
IDA
GO:0007186
G-protein coupled receptor protein signaling pathway
IDA
GO:0007267
cell-cell signaling
IC
GO:0008284
positive regulation of cell proliferation
IDA
GO:0008286
insulin receptor signaling pathway
TAS
GO:0008543
fibroblast growth factor receptor signaling pathway
TAS
GO:0014068
positive regulation of phosphatidylinositol 3-kinase cascade
IDA
GO:0015758
glucose transport
IDA
GO:0022898
regulation of transmembrane transporter activity
IDA
GO:0030307
positive regulation of cell growth
NAS
GO:0030335
positive regulation of cell migration
ISS
GO:0031018
endocrine pancreas development
TAS
GO:0031954
positive regulation of protein autophosphorylation
ISS
GO:0032148
activation of protein kinase B activity
IDA
GO:0032270
positive regulation of cellular protein metabolic process
IMP
GO:0032880
regulation of protein localization
IDA
GO:0033861
negative regulation of NAD(P)H oxidase activity
IDA
GO:0042060
wound healing
IDA
GO:0042177
negative regulation of protein catabolic process
IDA
GO:0042593
glucose homeostasis
IMP
GO:0043066
negative regulation of apoptosis
NAS
GO:0043410
positive regulation of MAPKKK cascade
IDA
GO:0045429
positive regulation of nitric oxide biosynthetic process
NAS
GO:0045597
positive regulation of cell differentiation
NAS
GO:0045721
negative regulation of gluconeogenesis
NAS
GO:0045725
positive regulation of glycogen biosynthetic process
IDA
GO:0045740
positive regulation of DNA replication
IDA
GO:0045818
negative regulation of glycogen catabolic process
IMP
GO:0045821
positive regulation of glycolysis
IDA
GO:0045821
positive regulation of glycolysis
IMP
GO:0045840
positive regulation of mitosis
IDA
GO:0045861
negative regulation of proteolysis
IMP
GO:0045908
negative regulation of vasodilation
NAS
GO:0045909
positive regulation of vasodilation
NAS
GO:0045922
negative regulation of fatty acid metabolic process
IMP
GO:0046326
positive regulation of glucose import
IDA
GO:0046628
positive regulation of insulin receptor signaling pathway
IDA
GO:0046631
alpha-beta T cell activation
IDA
GO:0046889
positive regulation of lipid biosynthetic process
NAS
GO:0050708
regulation of protein secretion
IDA
GO:0050709
negative regulation of protein secretion
IDA
GO:0050715
positive regulation of cytokine secretion
IDA
GO:0050731
positive regulation of peptidyl-tyrosine phosphorylation
IDA
GO:0050796
regulation of insulin secretion
TAS
GO:0050995
negative regulation of lipid catabolic process
NAS
GO:0051000
positive regulation of nitric-oxide synthase activity
NAS
GO:0051092
positive regulation of NF-kappaB transcription factor activity
IDA
GO:0051897
positive regulation of protein kinase B signaling cascade
IDA
GO:0055089
fatty acid homeostasis
IMP
GO:0060266
negative regulation of respiratory burst involved in inflammatory response
IDA
GO:0060267
positive regulation of respiratory burst
IDA
GO:2000252
negative regulation of feeding behavior
IDA
cellular_component
GO:0005576
extracellular region
IC
GO:0005576
extracellular region
IEA
GO:0005576
extracellular region
TAS
GO:0005615
extracellular space
IDA
GO:0005788
endoplasmic reticulum lumen
TAS
GO:0005796
Golgi lumen
TAS
GO:0030141
stored secretory granule
TAS
GO:0031904
endosome lumen
TAS
molecular_function
GO:0005158
insulin receptor binding
IDA
GO:0005158
insulin receptor binding
IPI
GO:0005159
insulin-like growth factor receptor binding
IPI
GO:0005179
hormone activity
IC
GO:0005179
hormone activity
IEA
GO:0005179
hormone activity
IMP
GO:0005179
hormone activity
NAS
GO:0005515
protein binding
IPI
Protein-protein interaction details for INS (
Homo sapiens
)
(Information is obtained from BioGRID)
Not available