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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IL6R (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0002384 hepatic immune response TAS GO:0002446 neutrophil mediated immunity IC GO:0002548 monocyte chemotaxis IC GO:0002690 positive regulation of leukocyte chemotaxis IC GO:0002690 positive regulation of leukocyte chemotaxis TAS GO:0006953 acute-phase response TAS GO:0008284 positive regulation of cell proliferation IDA GO:0008284 positive regulation of cell proliferation IMP GO:0010332 response to gamma radiation IEA GO:0010536 positive regulation of activation of Janus kinase activity IDA GO:0016049 cell growth IEA GO:0019221 cytokine-mediated signaling pathway IDA GO:0031018 endocrine pancreas development IC GO:0031018 endocrine pancreas development IMP GO:0032496 response to lipopolysaccharide IEA GO:0032717 negative regulation of interleukin-8 production IEP GO:0032722 positive regulation of chemokine production IDA GO:0032722 positive regulation of chemokine production IEP GO:0032755 positive regulation of interleukin-6 production IDA GO:0032966 negative regulation of collagen biosynthetic process IDA GO:0034097 response to cytokine stimulus IDA GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein IMP GO:0042981 regulation of apoptosis TAS GO:0043410 positive regulation of MAPKKK cascade IDA GO:0043434 response to peptide hormone stimulus IEA GO:0045471 response to ethanol IEA GO:0045669 positive regulation of osteoblast differentiation TAS GO:0045768 positive regulation of anti-apoptosis IMP GO:0046427 positive regulation of JAK-STAT cascade IEA GO:0048661 positive regulation of smooth muscle cell proliferation IDA GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IDA GO:0050829 defense response to Gram-negative bacterium IEP GO:0050830 defense response to Gram-positive bacterium IEP GO:0051092 positive regulation of NF-kappaB transcription factor activity IDA GO:0051384 response to glucocorticoid stimulus IEA GO:0051591 response to cAMP IEA GO:0070102 interleukin-6-mediated signaling pathway IDA GO:0070102 interleukin-6-mediated signaling pathway IMP GO:0070120 ciliary neurotrophic factor-mediated signaling pathway IMP cellular_component GO:0005576 extracellular region IDA GO:0005576 extracellular region TAS GO:0005615 extracellular space IDA GO:0005615 extracellular space IEA GO:0005886 plasma membrane TAS GO:0005896 interleukin-6 receptor complex IDA GO:0009986 cell surface IEA GO:0016021 integral to membrane IEA GO:0016323 basolateral plasma membrane IEA GO:0016324 apical plasma membrane IDA molecular_function GO:0004872 receptor activity IEA GO:0004897 ciliary neurotrophic factor receptor activity IMP GO:0004915 interleukin-6 receptor activity IDA GO:0005138 interleukin-6 receptor binding IPI GO:0005515 protein binding IPI GO:0019899 enzyme binding IPI GO:0019981 interleukin-6 binding IPI GO:0042803 protein homodimerization activity IPI GO:0070119 ciliary neurotrophic factor binding IPI

Protein-protein interaction details for IL6R (Homo sapiens) (Information is obtained from BioGRID)

Not available