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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IL6R (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3570
Official gene symbolIL6R
Full nameinterleukin 6 receptor
Aliases,CD126,IL-6R-1,IL-6R-alpha,IL6RA,MGC104991,
Gene summaryInterleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. The protein encoded by this gene is a subunit of the receptor complex for IL6. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q21
Gene position154377669 - 154440188  Map Viewer
Gene orientationplus
Gene size62520 bp
Gene sequence
OMIM ID147880