| Entrez gene ID | | 8622 |
| Official gene symbol | | PDE8B |
| Full name | | phosphodiesterase 8B |
| Aliases | | ,ADSD,FLJ11212,PPNAD3, |
| Gene summary | | The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene. |
| Location | | Chromosome: 5 Locus: 5q13.3 |
| Gene position | | 76506706 - 76724081 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 217376 bp |
| Gene sequence |
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| OMIM ID | | 603390 |
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