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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PDE8B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8622
Official gene symbolPDE8B
Full namephosphodiesterase 8B
Aliases,ADSD,FLJ11212,PPNAD3,
Gene summaryThe protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.
LocationChromosome: 5   Locus: 5q13.3
Gene position76506706 - 76724081  Map Viewer
Gene orientationplus
Gene size217376 bp
Gene sequence
OMIM ID603390