| Entrez gene ID | | 4688 |
| Official gene symbol | | NCF2 |
| Full name | | neutrophil cytosolic factor 2 |
| Aliases | | ,FLJ93058,NCF-2,NOXA2,P67-PHOX,P67PHOX, |
| Gene summary | | This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq] |
| Location | | Chromosome: 1 Locus: 1q25 |
| Gene position | | 183560056 - 183524697 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 35360 bp |
| Gene sequence |
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| OMIM ID | | 608515 |
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