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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for RIPK1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0002756 MyD88-independent toll-like receptor signaling pathway TAS GO:0006915 apoptosis IDA GO:0006915 apoptosis TAS GO:0006917 induction of apoptosis IMP GO:0006919 activation of caspase activity TAS GO:0007165 signal transduction IEA GO:0007257 activation of JUN kinase activity TAS GO:0008063 Toll signaling pathway TAS GO:0008624 induction of apoptosis by extracellular signals TAS GO:0008633 activation of pro-apoptotic gene products TAS GO:0010940 positive regulation of necrotic cell death IMP GO:0032757 positive regulation of interleukin-8 production IDA GO:0032760 positive regulation of tumor necrosis factor production IDA GO:0033209 tumor necrosis factor-mediated signaling pathway IC GO:0034138 toll-like receptor 3 signaling pathway TAS GO:0034142 toll-like receptor 4 signaling pathway TAS GO:0034612 response to tumor necrosis factor IMP GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade IEP GO:0045087 innate immune response TAS GO:0045768 positive regulation of anti-apoptosis TAS GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0046777 protein autophosphorylation IDA GO:0051092 positive regulation of NF-kappaB transcription factor activity IMP GO:0060555 induction of necroptosis by extracellular signals IMP GO:0070926 regulation of ATP:ADP antiporter activity IMP GO:2000379 positive regulation of reactive oxygen species metabolic process TAS cellular_component GO:0005737 cytoplasm IDA GO:0005739 mitochondrion IDA GO:0005829 cytosol TAS GO:0005886 plasma membrane TAS GO:0010008 endosome membrane TAS GO:0031264 death-inducing signaling complex IDA GO:0043235 receptor complex IDA GO:0045121 membrane raft IEA molecular_function GO:0000166 nucleotide binding IEA GO:0004672 protein kinase activity IDA GO:0004674 protein serine/threonine kinase activity IDA GO:0005123 death receptor binding IPI GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0070513 death domain binding IPI

Protein-protein interaction details for RIPK1 (Homo sapiens) (Information is obtained from BioGRID)

Not available