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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CASP8 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001525angiogenesisIEA
GO:0001841neural tube formationIEA
GO:0002218activation of innate immune responseTAS
GO:0006508proteolysisIDA
GO:0006508proteolysisIEA
GO:0006915apoptosisIGI
GO:0006915apoptosisTAS
GO:0006919activation of caspase activityTAS
GO:0006921cellular component disassembly involved in apoptosisTAS
GO:0007507heart developmentIEA
GO:0008624induction of apoptosis by extracellular signalsIMP
GO:0008624induction of apoptosis by extracellular signalsTAS
GO:0008629induction of apoptosis by intracellular signalsTAS
GO:0008633activation of pro-apoptotic gene productsTAS
GO:0009409response to coldIEA
GO:0030225macrophage differentiationIEA
GO:0032025response to cobalt ionIEA
GO:0032355response to estradiol stimulusIEA
GO:0032496response to lipopolysaccharideIEA
GO:0034612response to tumor necrosis factorIMP
GO:0042981regulation of apoptosisIEA
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cascadeIEP
GO:0045087innate immune responseTAS
GO:0045471response to ethanolIEA
GO:0046677response to antibioticIEA
GO:0051291protein heterooligomerizationIEA
GO:0051603proteolysis involved in cellular protein catabolic processIMP
GO:0070423nucleotide-binding oligomerization domain containing signaling pathwayTAS
GO:0071260cellular response to mechanical stimulusIEP
cellular_component
GO:0005634nucleusIDA
GO:0005634nucleusIEA
GO:0005730nucleolusIDA
GO:0005737cytoplasmIDA
GO:0005737cytoplasmIEA
GO:0005739mitochondrionIDA
GO:0005739mitochondrionIEA
GO:0005741mitochondrial outer membraneTAS
GO:0005813centrosomeIDA
GO:0005829cytosolIEA
GO:0005829cytosolTAS
GO:0005856cytoskeletonTAS
GO:0030690Noc1p-Noc2p complexIEA
GO:0031264death-inducing signaling complexIDA
GO:0031265CD95 death-inducing signaling complexIEA
GO:0043005neuron projectionIEA
GO:0043234protein complexIEA
GO:0044297cell bodyIEA
GO:0045121membrane raftIEA
molecular_function
GO:0004197cysteine-type endopeptidase activityIEA
GO:0004197cysteine-type endopeptidase activityTAS
GO:0005164tumor necrosis factor receptor bindingIEA
GO:0005515protein bindingIPI
GO:0008233peptidase activityIEA
GO:0008234cysteine-type peptidase activityTAS
GO:0042802identical protein bindingIPI

Protein-protein interaction details for CASP8 (Homo sapiens)
(Information is obtained from BioGRID)
Not available