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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ITCH (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001558 regulation of cell growth NAS GO:0002218 activation of innate immune response TAS GO:0002669 positive regulation of T cell anergy IEA GO:0006464 protein modification process IEA GO:0006511 ubiquitin-dependent protein catabolic process IDA GO:0006511 ubiquitin-dependent protein catabolic process NAS GO:0006954 inflammatory response NAS GO:0009615 response to virus IEA GO:0016567 protein ubiquitination IDA GO:0016567 protein ubiquitination NAS GO:0032088 negative regulation of NF-kappaB transcription factor activity IEA GO:0032088 negative regulation of NF-kappaB transcription factor activity ISS GO:0032480 negative regulation of type I interferon production TAS GO:0035519 protein K29-linked ubiquitination IDA GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process IBA GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process IEA GO:0043066 negative regulation of apoptosis IMP GO:0044419 interspecies interaction between organisms IEA GO:0045087 innate immune response TAS GO:0045732 positive regulation of protein catabolic process IEA GO:0046329 negative regulation of JNK cascade IEA GO:0046329 negative regulation of JNK cascade ISS GO:0046642 negative regulation of alpha-beta T cell proliferation IEA GO:0046718 entry of virus into host cell TAS GO:0050687 negative regulation of defense response to virus IEA GO:0050687 negative regulation of defense response to virus IMP GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway TAS GO:0070534 protein K63-linked ubiquitination IDA GO:0070936 protein K48-linked ubiquitination IDA GO:0070936 protein K48-linked ubiquitination IEA GO:0090085 regulation of protein deubiquitination IEA GO:0090085 regulation of protein deubiquitination ISS cellular_component GO:0005622 intracellular IEA GO:0005624 membrane fraction IEA GO:0005634 nucleus IEA GO:0005737 cytoplasm IDA GO:0005737 cytoplasm IEA GO:0005829 cytosol TAS GO:0005886 plasma membrane IDA GO:0005938 cell cortex IEA GO:0031410 cytoplasmic vesicle IEA molecular_function GO:0004842 ubiquitin-protein ligase activity IDA GO:0004842 ubiquitin-protein ligase activity NAS GO:0005515 protein binding IPI GO:0016874 ligase activity IEA GO:0016881 acid-amino acid ligase activity IEA GO:0043021 ribonucleoprotein binding IPI GO:0045236 CXCR chemokine receptor binding IPI

Protein-protein interaction details for ITCH (Homo sapiens) (Information is obtained from BioGRID)

Not available