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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TRAF2 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0002726positive regulation of T cell cytokine productionIMP
GO:0006461protein complex assemblyTAS
GO:0006915apoptosisTAS
GO:0006919activation of caspase activityTAS
GO:0007165signal transductionIEA
GO:0007165signal transductionNAS
GO:0007250activation of NF-kappaB-inducing kinase activityIMP
GO:0008624induction of apoptosis by extracellular signalsTAS
GO:0008633activation of pro-apoptotic gene productsTAS
GO:0030163protein catabolic processIEA
GO:0032743positive regulation of interleukin-2 productionIMP
GO:0033209tumor necrosis factor-mediated signaling pathwayIDA
GO:0033209tumor necrosis factor-mediated signaling pathwayIEA
GO:0034351negative regulation of glial cell apoptosisIEA
GO:0042981regulation of apoptosisIDA
GO:0042981regulation of apoptosisIEA
GO:0043507positive regulation of JUN kinase activityIDA
GO:0043623cellular protein complex assemblyIEA
GO:0043623cellular protein complex assemblyISS
GO:0045087innate immune responseTAS
GO:0046328regulation of JNK cascadeIEA
GO:0050870positive regulation of T cell activationIC
GO:0051023regulation of immunoglobulin secretionIEA
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activityIMP
GO:0051092positive regulation of NF-kappaB transcription factor activityIEA
GO:0051092positive regulation of NF-kappaB transcription factor activityIMP
GO:0051865protein autoubiquitinationIDA
GO:0051865protein autoubiquitinationTAS
GO:0070207protein homotrimerizationIPI
GO:0070534protein K63-linked ubiquitinationIDA
cellular_component
GO:0005737cytoplasmIDA
GO:0005737cytoplasmIEA
GO:0005829cytosolTAS
GO:0005938cell cortexIEA
GO:0009898internal side of plasma membraneIEA
GO:0009898internal side of plasma membraneISS
GO:0035631CD40 receptor complexIEA
GO:0035631CD40 receptor complexISS
GO:0043234protein complexIEA
GO:0045121membrane raftIEA
molecular_function
GO:0004842ubiquitin-protein ligase activityIDA
GO:0004871signal transducer activityNAS
GO:0004872receptor activityIEA
GO:0005102receptor bindingIEA
GO:0005174CD40 receptor bindingIEA
GO:0005174CD40 receptor bindingISS
GO:0005515protein bindingIPI
GO:0008270zinc ion bindingIEA
GO:0016874ligase activityIEA
GO:0019899enzyme bindingIPI
GO:0031435mitogen-activated protein kinase kinase kinase bindingIEA
GO:0042802identical protein bindingIPI
GO:0046625sphingolipid bindingIDA
GO:0046872metal ion bindingIEA

Protein-protein interaction details for TRAF2 (Homo sapiens)
(Information is obtained from BioGRID)
Not available