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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for THBS1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000187 activation of MAPK activity IMP GO:0001666 response to hypoxia NAS GO:0001937 negative regulation of endothelial cell proliferation IDA GO:0001937 negative regulation of endothelial cell proliferation IMP GO:0001953 negative regulation of cell-matrix adhesion IDA GO:0002040 sprouting angiogenesis IMP GO:0002544 chronic inflammatory response IEP GO:0002576 platelet degranulation TAS GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II IDA GO:0002605 negative regulation of dendritic cell antigen processing and presentation IDA GO:0006916 anti-apoptosis TAS GO:0006917 induction of apoptosis IDA GO:0006955 immune response IEP GO:0007050 cell cycle arrest IDA GO:0007155 cell adhesion NAS GO:0007596 blood coagulation TAS GO:0009749 response to glucose stimulus IDA GO:0010595 positive regulation of endothelial cell migration IDA GO:0010596 negative regulation of endothelial cell migration IDA GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport IDA GO:0010751 negative regulation of nitric oxide mediated signal transduction IDA GO:0010754 negative regulation of cGMP-mediated signaling IDA GO:0010757 negative regulation of plasminogen activation IDA GO:0010759 positive regulation of macrophage chemotaxis ISS GO:0010763 positive regulation of fibroblast migration IDA GO:0016477 cell migration IDA GO:0016525 negative regulation of angiogenesis IDA GO:0018149 peptide cross-linking IDA GO:0030168 platelet activation TAS GO:0030194 positive regulation of blood coagulation IDA GO:0030335 positive regulation of cell migration IDA GO:0030335 positive regulation of cell migration IMP GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway IDA GO:0032026 response to magnesium ion IDA GO:0032570 response to progesterone stimulus TAS GO:0032695 negative regulation of interleukin-12 production IDA GO:0032914 positive regulation of transforming growth factor beta1 production ISS GO:0034605 cellular response to heat NAS GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway IDA GO:0042327 positive regulation of phosphorylation IMP GO:0042493 response to drug IEP GO:0042535 positive regulation of tumor necrosis factor biosynthetic process IDA GO:0043032 positive regulation of macrophage activation IDA GO:0043066 negative regulation of apoptosis IDA GO:0043154 negative regulation of caspase activity IDA GO:0043536 positive regulation of blood vessel endothelial cell migration IDA GO:0043537 negative regulation of blood vessel endothelial cell migration IDA GO:0043652 engulfment of apoptotic cell IDA GO:0045727 positive regulation of translation IDA GO:0045766 positive regulation of angiogenesis IMP GO:0050921 positive regulation of chemotaxis IDA GO:0051592 response to calcium ion IDA GO:0051895 negative regulation of focal adhesion assembly TAS GO:0051897 positive regulation of protein kinase B signaling cascade IDA GO:0051918 negative regulation of fibrinolysis IDA GO:2000379 positive regulation of reactive oxygen species metabolic process IDA cellular_component GO:0005576 extracellular region TAS GO:0005577 fibrinogen complex IDA GO:0005615 extracellular space IDA GO:0009897 external side of plasma membrane IDA GO:0030141 stored secretory granule IDA GO:0031012 extracellular matrix IDA GO:0031012 extracellular matrix TAS GO:0031091 platelet alpha granule IDA GO:0031093 platelet alpha granule lumen TAS molecular_function GO:0001786 phosphatidylserine binding IDA GO:0001948 glycoprotein binding NAS GO:0001968 fibronectin binding IDA GO:0005178 integrin binding IMP GO:0005198 structural molecule activity IEA GO:0005509 calcium ion binding NAS GO:0005515 protein binding IPI GO:0008201 heparin binding IDA GO:0030169 low-density lipoprotein particle binding IDA GO:0042802 identical protein binding NAS GO:0043236 laminin binding IDA GO:0043394 proteoglycan binding TAS GO:0043499 eukaryotic cell surface binding IDA GO:0048603 fibroblast growth factor 2 binding IDA GO:0050431 transforming growth factor beta binding ISS GO:0050431 transforming growth factor beta binding TAS GO:0070051 fibrinogen binding IDA GO:0070052 collagen V binding IDA

Protein-protein interaction details for THBS1 (Homo sapiens) (Information is obtained from BioGRID)

Not available