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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TGFB1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000060protein import into nucleus, translocationIDA
GO:0000122negative regulation of transcription from RNA polymerase II promoterIEA
GO:0001657ureteric bud developmentIEA
GO:0001666response to hypoxiaIEA
GO:0001763morphogenesis of a branching structureIEA
GO:0001933negative regulation of protein phosphorylationIDA
GO:0001934positive regulation of protein phosphorylationIDA
GO:0002028regulation of sodium ion transportIEA
GO:0002062chondrocyte differentiationIDA
GO:0002244hemopoietic progenitor cell differentiationIDA
GO:0002248connective tissue replacement involved in inflammatory response wound healingTAS
GO:0002460adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsIEA
GO:0002513tolerance induction to self antigenIEA
GO:0002576platelet degranulationTAS
GO:0006468protein phosphorylationISS
GO:0006611protein export from nucleusIDA
GO:0006754ATP biosynthetic processIDA
GO:0006796phosphate-containing compound metabolic processIDA
GO:0006874cellular calcium ion homeostasisIEA
GO:0006917induction of apoptosisIDA
GO:0006954inflammatory responseISS
GO:0007050cell cycle arrestIDA
GO:0007173epidermal growth factor receptor signaling pathwayIDA
GO:0007179transforming growth factor beta receptor signaling pathwayIDA
GO:0007179transforming growth factor beta receptor signaling pathwayISS
GO:0007179transforming growth factor beta receptor signaling pathwayTAS
GO:0007183SMAD protein complex assemblyIDA
GO:0007184SMAD protein import into nucleusIDA
GO:0007406negative regulation of neuroblast proliferationIEA
GO:0007435salivary gland morphogenesisIEP
GO:0007492endoderm developmentIEA
GO:0007565female pregnancyIEA
GO:0007568agingIEA
GO:0007596blood coagulationTAS
GO:0008156negative regulation of DNA replicationIMP
GO:0008219cell deathIEA
GO:0008284positive regulation of cell proliferationIDA
GO:0008284positive regulation of cell proliferationISS
GO:0008285negative regulation of cell proliferationIDA
GO:0008354germ cell migrationIEA
GO:0009314response to radiationIEA
GO:0009611response to woundingIEP
GO:0009749response to glucose stimulusIEA
GO:0009790embryo developmentIEA
GO:0009817defense response to fungus, incompatible interactionIEA
GO:0010628positive regulation of gene expressionIDA
GO:0010718positive regulation of epithelial to mesenchymal transitionIDA
GO:0010742macrophage derived foam cell differentiationIC
GO:0010763positive regulation of fibroblast migrationIDA
GO:0010800positive regulation of peptidyl-threonine phosphorylationIDA
GO:0010862positive regulation of pathway-restricted SMAD protein phosphorylationIDA
GO:0010936negative regulation of macrophage cytokine productionIDA
GO:0014070response to organic cyclic compoundIEA
GO:0016202regulation of striated muscle tissue developmentISS
GO:0017015regulation of transforming growth factor beta receptor signaling pathwayIDA
GO:0019048virus-host interactionTAS
GO:0019049evasion of host defenses by virusIDA
GO:0019058viral infectious cycleTAS
GO:0022408negative regulation of cell-cell adhesionIDA
GO:0030168platelet activationTAS
GO:0030279negative regulation of ossificationIEA
GO:0030308negative regulation of cell growthIDA
GO:0030334regulation of cell migrationTAS
GO:0030501positive regulation of bone mineralizationIEP
GO:0030879mammary gland developmentIEA
GO:0031065positive regulation of histone deacetylationIEA
GO:0031100organ regenerationIEA
GO:0031536positive regulation of exit from mitosisIEA
GO:0031575mitotic cell cycle G1/S transition checkpointIDA
GO:0032270positive regulation of cellular protein metabolic processIDA
GO:0032355response to estradiol stimulusIDA
GO:0032570response to progesterone stimulusIDA
GO:0032740positive regulation of interleukin-17 productionIDA
GO:0032801receptor catabolic processIDA
GO:0032943mononuclear cell proliferationIEA
GO:0032967positive regulation of collagen biosynthetic processIDA
GO:0032967positive regulation of collagen biosynthetic processIMP
GO:0033138positive regulation of peptidyl-serine phosphorylationIDA
GO:0033280response to vitamin DIEA
GO:0034616response to laminar fluid shear stressIEA
GO:0035066positive regulation of histone acetylationIEA
GO:0035307positive regulation of protein dephosphorylationIDA
GO:0042130negative regulation of T cell proliferationIEA
GO:0042306regulation of protein import into nucleusISS
GO:0042482positive regulation of odontogenesisIEA
GO:0042493response to drugIEA
GO:0042552myelinationIEA
GO:0043011myeloid dendritic cell differentiationIEA
GO:0043029T cell homeostasisIEA
GO:0043406positive regulation of MAP kinase activityIDA
GO:0043536positive regulation of blood vessel endothelial cell migrationIDA
GO:0043537negative regulation of blood vessel endothelial cell migrationIDA
GO:0043552positive regulation of phosphatidylinositol 3-kinase activityIDA
GO:0043932ossification involved in bone remodelingIEP
GO:0045066regulatory T cell differentiationIEA
GO:0045216cell-cell junction organizationIDA
GO:0045599negative regulation of fat cell differentiationIDA
GO:0045662negative regulation of myoblast differentiationIDA
GO:0045786negative regulation of cell cycleIDA
GO:0045892negative regulation of transcription, DNA-dependentIDA
GO:0045893positive regulation of transcription, DNA-dependentIDA
GO:0045893positive regulation of transcription, DNA-dependentISS
GO:0045930negative regulation of mitotic cell cycleIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0046732active induction of host immune response by virusTAS
GO:0048298positive regulation of isotype switching to IgA isotypesIDA
GO:0048535lymph node developmentISS
GO:0048565digestive tract developmentIEA
GO:0048642negative regulation of skeletal muscle tissue developmentIDA
GO:0048839inner ear developmentIEA
GO:0050679positive regulation of epithelial cell proliferationIEA
GO:0050680negative regulation of epithelial cell proliferationIMP
GO:0050714positive regulation of protein secretionIDA
GO:0050765negative regulation of phagocytosisIEA
GO:0050777negative regulation of immune responseIEA
GO:0050921positive regulation of chemotaxisIDA
GO:0051092positive regulation of NF-kappaB transcription factor activityIEA
GO:0051098regulation of bindingISS
GO:0051101regulation of DNA bindingISS
GO:0051152positive regulation of smooth muscle cell differentiationIEA
GO:0051280negative regulation of release of sequestered calcium ion into cytosolIEA
GO:0051781positive regulation of cell divisionIEA
GO:0051897positive regulation of protein kinase B signaling cascadeIDA
GO:0060364frontal suture morphogenesisIEA
GO:0060389pathway-restricted SMAD protein phosphorylationIDA
GO:0060391positive regulation of SMAD protein import into nucleusIDA
GO:0060744mammary gland branching involved in thelarcheIEA
GO:0060751branch elongation involved in mammary gland duct branchingIEA
GO:0060762regulation of branching involved in mammary gland duct morphogenesisIEA
GO:0070306lens fiber cell differentiationIEA
GO:0070723response to cholesterolIDA
GO:0071158positive regulation of cell cycle arrestIEA
GO:0071363cellular response to growth factor stimulusIEA
GO:0071549cellular response to dexamethasone stimulusIEA
GO:0090190positive regulation of branching involved in ureteric bud morphogenesisIEA
cellular_component
GO:0005576extracellular regionTAS
GO:0005578proteinaceous extracellular matrixISS
GO:0005615extracellular spaceIDA
GO:0005634nucleusIDA
GO:0005737cytoplasmIDA
GO:0005796Golgi lumenTAS
GO:0009986cell surfaceIEA
GO:0030141stored secretory granuleIEA
GO:0030424axonIEA
GO:0031093platelet alpha granule lumenTAS
GO:0043025neuronal cell bodyIEA
molecular_function
GO:0005114type II transforming growth factor beta receptor bindingIDA
GO:0005114type II transforming growth factor beta receptor bindingIPI
GO:0005515protein bindingIPI
GO:0008083growth factor activityIEA
GO:0042803protein homodimerization activityIEA
GO:0046982protein heterodimerization activityIEA
GO:0047485protein N-terminus bindingIEA

Protein-protein interaction details for TGFB1 (Homo sapiens)
(Information is obtained from BioGRID)
Not available