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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TCF7L2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IDA GO:0001568 blood vessel development IMP GO:0006351 transcription, DNA-dependent IDA GO:0006357 regulation of transcription from RNA polymerase II promoter IDA GO:0006916 anti-apoptosis IDA GO:0007050 cell cycle arrest IMP GO:0007420 brain development IBA GO:0008283 cell proliferation IMP GO:0009749 response to glucose stimulus ISS GO:0010909 positive regulation of heparan sulfate proteoglycan biosynthetic process IMP GO:0022008 neurogenesis IBA GO:0031016 pancreas development TAS GO:0032024 positive regulation of insulin secretion IDA GO:0032024 positive regulation of insulin secretion IMP GO:0032092 positive regulation of protein binding IDA GO:0032350 regulation of hormone metabolic process IDA GO:0042593 glucose homeostasis IDA GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity IDA GO:0043570 maintenance of DNA repeat elements IMP GO:0044334 canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition IMP GO:0045444 fat cell differentiation IDA GO:0045892 negative regulation of transcription, DNA-dependent IDA GO:0045892 negative regulation of transcription, DNA-dependent IMP GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0046827 positive regulation of protein export from nucleus IMP GO:0048625 myoblast cell fate commitment IDA GO:0048660 regulation of smooth muscle cell proliferation IMP GO:0048699 generation of neurons IBA GO:0051897 positive regulation of protein kinase B signaling cascade IMP GO:0060070 canonical Wnt receptor signaling pathway IC GO:0090090 negative regulation of canonical Wnt receptor signaling pathway IMP cellular_component GO:0005634 nucleus IDA GO:0005654 nucleoplasm IDA GO:0005667 transcription factor complex IBA GO:0016605 PML body IEA GO:0032993 protein-DNA complex IDA GO:0070369 beta-catenin-TCF7L2 complex IDA molecular_function GO:0003677 DNA binding IEA GO:0003682 chromatin binding IBA GO:0003700 sequence-specific DNA binding transcription factor activity IDA GO:0005515 protein binding IPI GO:0008013 beta-catenin binding IDA GO:0008013 beta-catenin binding IPI GO:0008134 transcription factor binding IPI GO:0019901 protein kinase binding IPI GO:0035257 nuclear hormone receptor binding IPI GO:0043565 sequence-specific DNA binding IDA GO:0043565 sequence-specific DNA binding IMP GO:0044212 transcription regulatory region DNA binding IDA GO:0045295 gamma-catenin binding IPI GO:0070016 armadillo repeat domain binding IPI

Protein-protein interaction details for TCF7L2 (Homo sapiens) (Information is obtained from BioGRID)

Not available