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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for BRCA1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000724double-strand break repair via homologous recombinationIDA
GO:0000724double-strand break repair via homologous recombinationTAS
GO:0006260DNA replicationIEA
GO:0006281DNA repairIEA
GO:0006281DNA repairTAS
GO:0006301postreplication repairIDA
GO:0006302double-strand break repairIMP
GO:0006302double-strand break repairTAS
GO:0006310DNA recombinationIEA
GO:0006357regulation of transcription from RNA polymerase II promoterTAS
GO:0006359regulation of transcription from RNA polymerase III promoterTAS
GO:0006915apoptosisTAS
GO:0006974response to DNA damage stimulusTAS
GO:0006978DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorTAS
GO:0007049cell cycleIEA
GO:0007059chromosome segregationIMP
GO:0007098centrosome cycleIEA
GO:0007420brain developmentIEA
GO:0007584response to nutrientIEA
GO:0008630DNA damage response, signal transduction resulting in induction of apoptosisIDA
GO:0009048dosage compensation, by inactivation of X chromosomeIEA
GO:0010212response to ionizing radiationIMP
GO:0016567protein ubiquitinationIDA
GO:0030521androgen receptor signaling pathwayNAS
GO:0031398positive regulation of protein ubiquitinationIDA
GO:0031572G2/M transition DNA damage checkpointIMP
GO:0032355response to estradiol stimulusIEA
GO:0033993response to lipidIEA
GO:0034446substrate adhesion-dependent cell spreadingIDA
GO:0035066positive regulation of histone acetylationIDA
GO:0042127regulation of cell proliferationTAS
GO:0042981regulation of apoptosisTAS
GO:0043009chordate embryonic developmentIEA
GO:0043627response to estrogen stimulusIDA
GO:0045717negative regulation of fatty acid biosynthetic processIMP
GO:0045739positive regulation of DNA repairIMP
GO:0045892negative regulation of transcription, DNA-dependentIDA
GO:0045893positive regulation of transcription, DNA-dependentNAS
GO:0045893positive regulation of transcription, DNA-dependentTAS
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIMP
GO:0046600negative regulation of centriole replicationNAS
GO:0051571positive regulation of histone H3-K4 methylationIDA
GO:0051573negative regulation of histone H3-K9 methylationIDA
GO:0051865protein autoubiquitinationIDA
GO:0070512positive regulation of histone H4-K20 methylationIDA
GO:0071158positive regulation of cell cycle arrestIDA
GO:0071681cellular response to indole-3-methanolIDA
GO:0085020protein K6-linked ubiquitinationIDA
GO:2000145regulation of cell motilityIDA
GO:2000617positive regulation of histone H3-K9 acetylationIDA
GO:2000620positive regulation of histone H4-K16 acetylationIDA
cellular_component
GO:0000151ubiquitin ligase complexNAS
GO:0000794condensed nuclear chromosomeIEA
GO:0001726ruffleIDA
GO:0005622intracellularIEA
GO:0005634nucleusIDA
GO:0005634nucleusIEA
GO:0005654nucleoplasmTAS
GO:0005737cytoplasmIEA
GO:0005759mitochondrial matrixIEA
GO:0005886plasma membraneIDA
GO:0005925focal adhesionIDA
GO:0008274gamma-tubulin ring complexNAS
GO:0030529ribonucleoprotein complexIDA
GO:0031436BRCA1-BARD1 complexIDA
GO:0031941filamentous actinIDA
GO:0043234protein complexIDA
GO:0070531BRCA1-A complexIDA
molecular_function
GO:0003677DNA bindingIEA
GO:0003677DNA bindingTAS
GO:0003684damaged DNA bindingIEA
GO:0003713transcription coactivator activityNAS
GO:0003723RNA bindingIDA
GO:0004842ubiquitin-protein ligase activityIDA
GO:0005515protein bindingIPI
GO:0008270zinc ion bindingIEA
GO:0015631tubulin bindingNAS
GO:0016874ligase activityIEA
GO:0019899enzyme bindingIPI
GO:0031625ubiquitin protein ligase bindingIPI
GO:0044212transcription regulatory region DNA bindingIDA
GO:0046872metal ion bindingIEA
GO:0050681androgen receptor bindingNAS

Protein-protein interaction details for BRCA1 (Homo sapiens)
(Information is obtained from BioGRID)
Not available