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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SHH (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000122negative regulation of transcription from RNA polymerase II promoterIEA
GO:0001569patterning of blood vesselsISS
GO:0001570vasculogenesisISS
GO:0001656metanephros developmentISS
GO:0001658branching involved in ureteric bud morphogenesisISS
GO:0001666response to hypoxiaIEA
GO:0001708cell fate specificationISS
GO:0001755neural crest cell migrationISS
GO:0001841neural tube formationIEA
GO:0001944vasculature developmentIEA
GO:0001947heart loopingISS
GO:0002052positive regulation of neuroblast proliferationIEA
GO:0002076osteoblast developmentIEA
GO:0002320lymphoid progenitor cell differentiationIMP
GO:0003140determination of left/right asymmetry in lateral mesodermISS
GO:0006897endocytosisIEA
GO:0007165signal transductionIDA
GO:0007224smoothened signaling pathwayIEP
GO:0007224smoothened signaling pathwayISS
GO:0007228positive regulation of hh target transcription factor activityISS
GO:0007267cell-cell signalingIEA
GO:0007267cell-cell signalingISS
GO:0007275multicellular organismal developmentIEA
GO:0007389pattern specification processISS
GO:0007398ectoderm developmentIEA
GO:0007405neuroblast proliferationISS
GO:0007411axon guidanceISS
GO:0007417central nervous system developmentISS
GO:0007418ventral midline developmentTAS
GO:0007442hindgut morphogenesisIEA
GO:0007502digestive tract mesoderm developmentIEA
GO:0007507heart developmentISS
GO:0007596blood coagulationIEA
GO:0008209androgen metabolic processISS
GO:0008219cell deathIEA
GO:0008284positive regulation of cell proliferationISS
GO:0009790embryo developmentISS
GO:0009952anterior/posterior pattern specificationIEA
GO:0009953dorsal/ventral pattern formationISS
GO:0010243response to organic nitrogenIEA
GO:0014003oligodendrocyte developmentIEA
GO:0014706striated muscle tissue developmentIEA
GO:0014858positive regulation of skeletal muscle cell proliferationIEA
GO:0014902myotube differentiationIEA
GO:0016539intein-mediated protein splicingIEA
GO:0021513spinal cord dorsal/ventral patterningIEA
GO:0021521ventral spinal cord interneuron specificationIEA
GO:0021904dorsal/ventral neural tube patterningIEA
GO:0021938smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferationIEA
GO:0021940positive regulation of cerebellar granule cell precursor proliferationIEA
GO:0021978telencephalon regionalizationIEA
GO:0030010establishment of cell polarityIEA
GO:0030162regulation of proteolysisISS
GO:0030177positive regulation of Wnt receptor signaling pathwayIEA
GO:0030324lung developmentISS
GO:0030326embryonic limb morphogenesisISS
GO:0030336negative regulation of cell migrationISS
GO:0030539male genitalia developmentISS
GO:0030850prostate gland developmentISS
GO:0030856regulation of epithelial cell differentiationIEA
GO:0030878thyroid gland developmentIEA
GO:0030900forebrain developmentISS
GO:0030901midbrain developmentISS
GO:0030902hindbrain developmentISS
GO:0031016pancreas developmentIEA
GO:0031069hair follicle morphogenesisIEA
GO:0032355response to estradiol stimulusIEA
GO:0032435negative regulation of proteasomal ubiquitin-dependent protein catabolic processIEA
GO:0032526response to retinoic acidIEA
GO:0033077T cell differentiation in thymusISS
GO:0033089positive regulation of T cell differentiation in thymusISS
GO:0033092positive regulation of immature T cell proliferation in thymusISS
GO:0034244negative regulation of transcription elongation from RNA polymerase II promoterIEA
GO:0034504protein localization to nucleusIEA
GO:0035115embryonic forelimb morphogenesisIEA
GO:0035116embryonic hindlimb morphogenesisIEA
GO:0042127regulation of cell proliferationISS
GO:0042130negative regulation of T cell proliferationIEA
GO:0042307positive regulation of protein import into nucleusIEA
GO:0042475odontogenesis of dentine-containing toothIEA
GO:0042733embryonic digit morphogenesisISS
GO:0043010camera-type eye developmentIEA
GO:0043066negative regulation of apoptosisIEA
GO:0043369CD4-positive or CD8-positive, alpha-beta T cell lineage commitmentIDA
GO:0043587tongue morphogenesisIEA
GO:0043588skin developmentIEA
GO:0045059positive thymic T cell selectionISS
GO:0045060negative thymic T cell selectionISS
GO:0045109intermediate filament organizationIEA
GO:0045445myoblast differentiationIEA
GO:0045471response to ethanolIEA
GO:0045596negative regulation of cell differentiationISS
GO:0045880positive regulation of smoothened signaling pathwayISS
GO:0045893positive regulation of transcription, DNA-dependentIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIEA
GO:0046534positive regulation of photoreceptor cell differentiationIEA
GO:0046638positive regulation of alpha-beta T cell differentiationISS
GO:0046639negative regulation of alpha-beta T cell differentiationIEA
GO:0048468cell developmentISS
GO:0048538thymus developmentISS
GO:0048557embryonic digestive tract morphogenesisIEA
GO:0048568embryonic organ developmentIEA
GO:0048589developmental growthIEA
GO:0048617embryonic foregut morphogenesisIEA
GO:0048643positive regulation of skeletal muscle tissue developmentIEA
GO:0048645organ formationIEA
GO:0048663neuron fate commitmentISS
GO:0048678response to axon injuryIEA
GO:0048706embryonic skeletal system developmentIEA
GO:0048714positive regulation of oligodendrocyte differentiationIEA
GO:0048754branching morphogenesis of a tubeISS
GO:0048808male genitalia morphogenesisIEA
GO:0048839inner ear developmentIEA
GO:0048859formation of anatomical boundaryIEA
GO:0048864stem cell developmentISS
GO:0051155positive regulation of striated muscle cell differentiationIEA
GO:0060020Bergmann glial cell differentiationIEA
GO:0060021palate developmentIEA
GO:0060173limb developmentIEA
GO:0060174limb bud formationIEA
GO:0060406positive regulation of penile erectionIEA
GO:0060428lung epithelium developmentIEA
GO:0060439trachea morphogenesisIEA
GO:0060445branching involved in salivary gland morphogenesisIEA
GO:0060447bud outgrowth involved in lung branchingIEA
GO:0060458right lung developmentIEA
GO:0060459left lung developmentIEA
GO:0060463lung lobe morphogenesisIEA
GO:0060484lung-associated mesenchyme developmentIEA
GO:0060516primary prostatic bud elongationIEA
GO:0060523prostate epithelial cord elongationIEA
GO:0060662salivary gland cavitationIEA
GO:0060664epithelial cell proliferation involved in salivary gland morphogenesisIEA
GO:0060685regulation of prostatic bud formationIEA
GO:0060738epithelial-mesenchymal signaling involved in prostate gland developmentIDA
GO:0060769positive regulation of epithelial cell proliferation involved in prostate gland developmentIEA
GO:0060782regulation of mesenchymal cell proliferation involved in prostate gland developmentIEA
GO:0060783mesenchymal smoothened signaling pathway involved in prostate gland developmentIEA
GO:0060840artery developmentIEA
GO:0060916mesenchymal cell proliferation involved in lung developmentIEA
GO:0061053somite developmentISS
GO:0061056sclerotome developmentIDA
GO:0070447positive regulation of oligodendrocyte progenitor proliferationIEA
GO:0071285cellular response to lithium ionIEA
GO:0072001renal system developmentIEP
GO:0072136metanephric mesenchymal cell proliferation involved in metanephros developmentISS
GO:0080125multicellular structure septum developmentIEA
GO:0090090negative regulation of canonical Wnt receptor signaling pathwayIEA
GO:2000062negative regulation of ureter smooth muscle cell differentiationISS
GO:2000063positive regulation of ureter smooth muscle cell differentiationISS
GO:2000357negative regulation of kidney smooth muscle cell differentiationISS
GO:2000358positive regulation of kidney smooth muscle cell differentiationISS
GO:2000729positive regulation of mesenchymal cell proliferation involved in ureter developmentISS
cellular_component
GO:0005576extracellular regionIEA
GO:0005615extracellular spaceIDA
GO:0005615extracellular spaceISS
GO:0005624membrane fractionIEA
GO:0005634nucleusIEA
GO:0005783endoplasmic reticulumIEA
GO:0005794Golgi apparatusIEA
GO:0005886plasma membraneIEA
GO:0009986cell surfaceISS
GO:0030133transport vesicleIEA
GO:0031012extracellular matrixIEA
GO:0045121membrane raftISS
molecular_function
GO:0001948glycoprotein bindingIEA
GO:0004871signal transducer activityIDA
GO:0005113patched bindingIDA
GO:0005509calcium ion bindingIDA
GO:0005515protein bindingIPI
GO:0005539glycosaminoglycan bindingIEA
GO:0008233peptidase activityIEA
GO:0008270zinc ion bindingIDA
GO:0043237laminin-1 bindingISS

Protein-protein interaction details for SHH (Homo sapiens)
(Information is obtained from BioGRID)
Not available