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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PTEN (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000079regulation of cyclin-dependent protein kinase activityTAS
GO:0001525angiogenesisIEA
GO:0001933negative regulation of protein phosphorylationIDA
GO:0002902regulation of B cell apoptosisIEA
GO:0006470protein dephosphorylationIDA
GO:0006470protein dephosphorylationTAS
GO:0006629lipid metabolic processIEA
GO:0006917induction of apoptosisISS
GO:0007092activation of mitotic anaphase-promoting complex activityIDA
GO:0007417central nervous system developmentISS
GO:0007507heart developmentISS
GO:0008283cell proliferationTAS
GO:0008284positive regulation of cell proliferationIEA
GO:0008285negative regulation of cell proliferationIDA
GO:0008285negative regulation of cell proliferationIMP
GO:0008543fibroblast growth factor receptor signaling pathwayTAS
GO:0010975regulation of neuron projection developmentISS
GO:0016477cell migrationISS
GO:0030336negative regulation of cell migrationIMP
GO:0031647regulation of protein stabilityIMP
GO:0031658negative regulation of cyclin-dependent protein kinase activity involved in G1/SIDA
GO:0033032regulation of myeloid cell apoptosisIEA
GO:0035335peptidyl-tyrosine dephosphorylationIDA
GO:0043066negative regulation of apoptosisIEA
GO:0043542endothelial cell migrationIEA
GO:0046855inositol phosphate dephosphorylationIDA
GO:0046856phosphatidylinositol dephosphorylationIDA
GO:0048011nerve growth factor receptor signaling pathwayTAS
GO:0048015phosphatidylinositol-mediated signalingTAS
GO:0048738cardiac muscle tissue developmentIEA
GO:0050680negative regulation of epithelial cell proliferationIEA
GO:0050821protein stabilizationIDA
GO:0050852T cell receptor signaling pathwayTAS
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activityIMP
GO:0051895negative regulation of focal adhesion assemblyIMP
GO:0051898negative regulation of protein kinase B signaling cascadeIMP
GO:0060070canonical Wnt receptor signaling pathwayIDA
GO:0060736prostate gland growthIEA
GO:0090344negative regulation of cell agingIEA
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic processIDA
GO:2000134negative regulation of G1/S transition of mitotic cell cycleIDA
cellular_component
GO:0005634nucleusIDA
GO:0005737cytoplasmIDA
GO:0005737cytoplasmTAS
GO:0005829cytosolTAS
GO:0009898internal side of plasma membraneIDA
GO:0016605PML bodyIEA
GO:0043209myelin sheathIEA
GO:0043220Schmidt-Lanterman incisureIEA
molecular_function
GO:0000287magnesium ion bindingIEA
GO:0004438phosphatidylinositol-3-phosphatase activityIDA
GO:0004721phosphoprotein phosphatase activityIDA
GO:0004722protein serine/threonine phosphatase activityIDA
GO:0004725protein tyrosine phosphatase activityIDA
GO:0005515protein bindingIPI
GO:0008138protein tyrosine/serine/threonine phosphatase activityIEA
GO:0008289lipid bindingIEA
GO:0010997anaphase-promoting complex bindingIPI
GO:0016314phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activityIDA
GO:0016314phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activityTAS
GO:0016787hydrolase activityIEA
GO:0019899enzyme bindingIPI
GO:0030165PDZ domain bindingIPI
GO:0051717inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activityIDA
GO:0051800phosphatidylinositol-3,4-bisphosphate 3-phosphatase activityIDA

Protein-protein interaction details for PTEN (Homo sapiens)
(Information is obtained from BioGRID)
Not available