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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PML (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001666response to hypoxiaIDA
GO:0001932regulation of protein phosphorylationISS
GO:0002230positive regulation of defense response to virus by hostIMP
GO:0006461protein complex assemblyIDA
GO:0006605protein targetingIDA
GO:0006605protein targetingIMP
GO:0006917induction of apoptosisIDA
GO:0006917induction of apoptosisIEA
GO:0006919activation of caspase activityIEA
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrestISS
GO:0007050cell cycle arrestIDA
GO:0007050cell cycle arrestIEA
GO:0007179transforming growth factor beta receptor signaling pathwayIEA
GO:0007182common-partner SMAD protein phosphorylationIEA
GO:0007184SMAD protein import into nucleusIEA
GO:0007569cell agingIEA
GO:0008285negative regulation of cell proliferationIMP
GO:0008630DNA damage response, signal transduction resulting in induction of apoptosisIDA
GO:0009411response to UVIEA
GO:0009615response to virusIEA
GO:0010332response to gamma radiationIEA
GO:0010522regulation of calcium ion transport into cytosolISS
GO:0016525negative regulation of angiogenesisIMP
GO:0019221cytokine-mediated signaling pathwayTAS
GO:0030099myeloid cell differentiationIEA
GO:0030308negative regulation of cell growthIDA
GO:0030578PML body organizationIDA
GO:0030578PML body organizationIMP
GO:0031065positive regulation of histone deacetylationIDA
GO:0032211negative regulation of telomere maintenance via telomeraseIMP
GO:0032469endoplasmic reticulum calcium ion homeostasisISS
GO:0032938negative regulation of translation in response to oxidative stressIDA
GO:0034097response to cytokine stimulusIDA
GO:0042771DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosisISS
GO:0044419interspecies interaction between organismsIEA
GO:0045165cell fate commitmentIEA
GO:0045343regulation of MHC class I biosynthetic processIEA
GO:0045892negative regulation of transcription, DNA-dependentIDA
GO:0045930negative regulation of mitotic cell cycleIDA
GO:0048384retinoic acid receptor signaling pathwayIEA
GO:0050821protein stabilizationIDA
GO:0051457maintenance of protein location in nucleusIDA
GO:0051974negative regulation of telomerase activityIMP
GO:0060333interferon-gamma-mediated signaling pathwayTAS
GO:0060444branching involved in mammary gland duct morphogenesisIEA
GO:2000059negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic processIMP
cellular_component
GO:0005622intracellularIEA
GO:0005626insoluble fractionIDA
GO:0005634nucleusIDA
GO:0005654nucleoplasmIDA
GO:0005654nucleoplasmTAS
GO:0005730nucleolusIDA
GO:0005737cytoplasmIDA
GO:0005768endosomeIEA
GO:0005783endoplasmic reticulumIEA
GO:0005829cytosolISS
GO:0016020membraneIEA
GO:0016363nuclear matrixIDA
GO:0016363nuclear matrixIEA
GO:0016605PML bodyIDA
GO:0016605PML bodyTAS
GO:0031901early endosome membraneIEA
GO:0031965nuclear membraneIDA
GO:0042406extrinsic to endoplasmic reticulum membraneISS
molecular_function
GO:0003677DNA bindingIEA
GO:0003713transcription coactivator activityIDA
GO:0005515protein bindingIPI
GO:0008270zinc ion bindingIDA
GO:0008270zinc ion bindingIEA
GO:0031625ubiquitin protein ligase bindingIPI
GO:0032183SUMO bindingIPI
GO:0042803protein homodimerization activityIPI
GO:0046332SMAD bindingIEA
GO:0046872metal ion bindingIEA
GO:0046982protein heterodimerization activityIDA
GO:0050897cobalt ion bindingIDA

Protein-protein interaction details for PML (Homo sapiens)
(Information is obtained from BioGRID)
Not available