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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PLK1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000086G2/M transition of mitotic cell cycleTAS
GO:0000087M phase of mitotic cell cycleTAS
GO:0000088mitotic prophaseTAS
GO:0000236mitotic prometaphaseIEA
GO:0000236mitotic prometaphaseTAS
GO:0000278mitotic cell cycleTAS
GO:0000910cytokinesisTAS
GO:0006468protein phosphorylationIDA
GO:0006468protein phosphorylationNAS
GO:0007067mitosisIDA
GO:0007091mitotic metaphase/anaphase transitionTAS
GO:0007346regulation of mitotic cell cycleIMP
GO:0008283cell proliferationTAS
GO:0010800positive regulation of peptidyl-threonine phosphorylationIMP
GO:0016567protein ubiquitinationIDA
GO:0018105peptidyl-serine phosphorylationIDA
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic processTAS
GO:0031572G2/M transition DNA damage checkpointIDA
GO:0031648protein destabilizationIDA
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic processIMP
GO:0040038polar body extrusion after meiotic divisionsIEA
GO:0043393regulation of protein bindingIMP
GO:0045736negative regulation of cyclin-dependent protein kinase activityIMP
GO:0045862positive regulation of proteolysisIDA
GO:0046677response to antibioticIEA
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTAS
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTAS
GO:0051443positive regulation of ubiquitin-protein ligase activityIMP
GO:0051726regulation of cell cycleTAS
GO:0071168protein localization to chromatinIDA
GO:0090007regulation of mitotic anaphaseIMP
cellular_component
GO:0000776kinetochoreIDA
GO:0000777condensed chromosome kinetochoreIEA
GO:0000922spindle poleIDA
GO:0000922spindle poleIEA
GO:0000942condensed nuclear chromosome outer kinetochoreIDA
GO:0005634nucleusIDA
GO:0005634nucleusIEA
GO:0005654nucleoplasmTAS
GO:0005694chromosomeIEA
GO:0005737cytoplasmIEA
GO:0005813centrosomeIDA
GO:0005829cytosolTAS
GO:0005856cytoskeletonIEA
GO:0005876spindle microtubuleIDA
GO:0030496midbodyIDA
GO:0051233spindle midzoneIDA
GO:0051233spindle midzoneIEA
molecular_function
GO:0000166nucleotide bindingIEA
GO:0004672protein kinase activityIDA
GO:0004674protein serine/threonine kinase activityIDA
GO:0004674protein serine/threonine kinase activityIEA
GO:0004674protein serine/threonine kinase activityIMP
GO:0005515protein bindingIPI
GO:0005524ATP bindingIEA
GO:0010997anaphase-promoting complex bindingIPI
GO:0019901protein kinase bindingIPI
GO:0042801polo kinase kinase activityIDA

Protein-protein interaction details for PLK1 (Homo sapiens)
(Information is obtained from BioGRID)
Not available