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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PLEK (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0002244hemopoietic progenitor cell differentiationIEP
GO:0002576platelet degranulationIEP
GO:0002576platelet degranulationTAS
GO:0006904vesicle docking involved in exocytosisISS
GO:0007229integrin-mediated signaling pathwayIDA
GO:0007596blood coagulationTAS
GO:0010572positive regulation of platelet activationISS
GO:0010920negative regulation of inositol phosphate biosynthetic processIDA
GO:0010925positive regulation of inositol-polyphosphate 5-phosphatase activityIDA
GO:0030030cell projection organizationIDA
GO:0030168platelet activationTAS
GO:0030836positive regulation of actin filament depolymerizationIDA
GO:0030845inhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathwayIDA
GO:0030866cortical actin cytoskeleton organizationIDA
GO:0031529ruffle organizationIDA
GO:0031532actin cytoskeleton reorganizationIDA
GO:0032233positive regulation of actin filament bundle assemblyIDA
GO:0033625positive regulation of integrin activationISS
GO:0035556intracellular signal transductionIEA
GO:0045744negative regulation of G-protein coupled receptor protein signaling pathwayIDA
GO:0046488phosphatidylinositol metabolic processIDA
GO:0050849negative regulation of calcium-mediated signalingNAS
GO:0060305regulation of cell diameterIDA
GO:0070493thrombin receptor signaling pathwayIDA
GO:0070527platelet aggregationISS
GO:0070528protein kinase C signaling cascadeISS
GO:0070560protein secretion by plateletISS
cellular_component
GO:0005576extracellular regionTAS
GO:0005624membrane fractionIDA
GO:0005625soluble fractionIDA
GO:0005737cytoplasmIDA
GO:0005829cytosolTAS
GO:0032587ruffle membraneIDA
molecular_function
GO:0005080protein kinase C bindingIDA
GO:0005515protein bindingIPI
GO:0042803protein homodimerization activityIDA
GO:0043325phosphatidylinositol-3,4-bisphosphate bindingIDA

Protein-protein interaction details for PLEK (Homo sapiens)
(Information is obtained from BioGRID)
Not available