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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for LEF1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IEA GO:0001569 patterning of blood vessels IBA GO:0001649 osteoblast differentiation IEP GO:0001755 neural crest cell migration IBA GO:0001756 somitogenesis IBA GO:0001822 kidney development IEA GO:0001837 epithelial to mesenchymal transition ISS GO:0001944 vasculature development IEA GO:0002040 sprouting angiogenesis IBA GO:0006351 transcription, DNA-dependent IDA GO:0006917 induction of apoptosis IBA GO:0007155 cell adhesion IEA GO:0007420 brain development IBA GO:0008284 positive regulation of cell proliferation IDA GO:0010226 response to lithium ion IEA GO:0010628 positive regulation of gene expression IDA GO:0010718 positive regulation of epithelial to mesenchymal transition IMP GO:0014070 response to organic cyclic compound IEA GO:0016055 Wnt receptor signaling pathway IDA GO:0016202 regulation of striated muscle tissue development IBA GO:0021542 dentate gyrus development IBA GO:0021854 hypothalamus development IBA GO:0021861 forebrain radial glial cell differentiation IBA GO:0021873 forebrain neuroblast division IBA GO:0021879 forebrain neuron differentiation IBA GO:0021943 formation of radial glial scaffolds IBA GO:0022008 neurogenesis IBA GO:0022407 regulation of cell-cell adhesion IEA GO:0022408 negative regulation of cell-cell adhesion IDA GO:0022409 positive regulation of cell-cell adhesion IDA GO:0030111 regulation of Wnt receptor signaling pathway IEA GO:0030223 neutrophil differentiation IMP GO:0030307 positive regulation of cell growth IMP GO:0030326 embryonic limb morphogenesis IBA GO:0030335 positive regulation of cell migration IDA GO:0030335 positive regulation of cell migration IMP GO:0030509 BMP signaling pathway IBA GO:0030520 estrogen receptor signaling pathway IDA GO:0030854 positive regulation of granulocyte differentiation IDA GO:0030879 mammary gland development IBA GO:0031100 organ regeneration IEA GO:0032696 negative regulation of interleukin-13 production IDA GO:0032713 negative regulation of interleukin-4 production IDA GO:0032714 negative regulation of interleukin-5 production IDA GO:0033153 T cell receptor V(D)J recombination IEA GO:0042100 B cell proliferation IBA GO:0042475 odontogenesis of dentine-containing tooth IEA GO:0043066 negative regulation of apoptosis IMP GO:0043154 negative regulation of caspase activity IMP GO:0043392 negative regulation of DNA binding IDA GO:0043586 tongue development IEA GO:0043588 skin development IEA GO:0043923 positive regulation by host of viral transcription IDA GO:0043966 histone H3 acetylation IMP GO:0043967 histone H4 acetylation IMP GO:0045063 T-helper 1 cell differentiation ISS GO:0045843 negative regulation of striated muscle tissue development IEA GO:0045892 negative regulation of transcription, DNA-dependent IDA GO:0045892 negative regulation of transcription, DNA-dependent IMP GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045893 positive regulation of transcription, DNA-dependent IMP GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0046632 alpha-beta T cell differentiation IBA GO:0048069 eye pigmentation IBA GO:0048341 paraxial mesoderm formation IBA GO:0048468 cell development IEA GO:0048699 generation of neurons IBA GO:0048747 muscle fiber development IBA GO:0050909 sensory perception of taste IEA GO:0060021 palate development ISS GO:0060033 anatomical structure regression IEA GO:0060070 canonical Wnt receptor signaling pathway IDA GO:0060070 canonical Wnt receptor signaling pathway IMP GO:0060325 face morphogenesis IBA GO:0060326 cell chemotaxis IDA GO:0060561 apoptosis involved in morphogenesis IBA GO:0060710 chorio-allantoic fusion IBA GO:0061153 trachea gland development IBA GO:0071353 cellular response to interleukin-4 IDA GO:0071864 positive regulation of cell proliferation in bone marrow IMP GO:0071866 negative regulation of apoptosis in bone marrow IMP GO:0071895 odontoblast differentiation IBA GO:0071899 negative regulation of estrogen receptor binding IDA GO:0090068 positive regulation of cell cycle process IDA GO:0090090 negative regulation of canonical Wnt receptor signaling pathway IMP cellular_component GO:0005634 nucleus IC GO:0005634 nucleus IDA GO:0005667 transcription factor complex IDA GO:0005737 cytoplasm IDA GO:0032993 protein-DNA complex IDA molecular_function GO:0003677 DNA binding IEA GO:0003677 DNA binding ISS GO:0003682 chromatin binding IBA GO:0003700 sequence-specific DNA binding transcription factor activity IDA GO:0003705 sequence-specific distal enhancer binding RNA polymerase II transcription factor activity IBA GO:0005515 protein binding IPI GO:0008013 beta-catenin binding IPI GO:0008013 beta-catenin binding TAS GO:0008134 transcription factor binding IEA GO:0008301 DNA bending activity ISS GO:0030284 estrogen receptor activity IDA GO:0030331 estrogen receptor binding IDA GO:0035326 enhancer binding IDA GO:0042393 histone binding IPI GO:0043027 caspase inhibitor activity IMP GO:0043565 sequence-specific DNA binding IDA GO:0044212 transcription regulatory region DNA binding IDA GO:0045295 gamma-catenin binding IPI GO:0070016 armadillo repeat domain binding IPI GO:0070742 C2H2 zinc finger domain binding IPI

Protein-protein interaction details for LEF1 (Homo sapiens) (Information is obtained from BioGRID)

Not available