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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for Smad4 (
Rattus norvegicus
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0001658
branching involved in ureteric bud morphogenesis
ISO
GO:0001666
response to hypoxia
IEA
GO:0001666
response to hypoxia
ISO
GO:0001701
in utero embryonic development
IEA
GO:0001701
in utero embryonic development
ISO
GO:0001702
gastrulation with mouth forming second
IEA
GO:0001702
gastrulation with mouth forming second
ISO
GO:0001822
kidney development
IEA
GO:0001822
kidney development
ISO
GO:0006351
transcription, DNA-dependent
ISO
GO:0006357
regulation of transcription from RNA polymerase II promoter
ISO
GO:0007179
transforming growth factor beta receptor signaling pathway
ISO
GO:0007183
SMAD protein complex assembly
IEA
GO:0007183
SMAD protein complex assembly
ISO
GO:0007369
gastrulation
ISO
GO:0007492
endoderm development
IEA
GO:0007492
endoderm development
ISO
GO:0007498
mesoderm development
IEA
GO:0007498
mesoderm development
ISO
GO:0008283
cell proliferation
ISO
GO:0008285
negative regulation of cell proliferation
IEA
GO:0008285
negative regulation of cell proliferation
ISO
GO:0009952
anterior/posterior pattern specification
IEA
GO:0009952
anterior/posterior pattern specification
ISO
GO:0010718
positive regulation of epithelial to mesenchymal transition
ISO
GO:0010862
positive regulation of pathway-restricted SMAD protein phosphorylation
ISO
GO:0014033
neural crest cell differentiation
ISO
GO:0017015
regulation of transforming growth factor beta receptor signaling pathway
ISO
GO:0030308
negative regulation of cell growth
IEA
GO:0030308
negative regulation of cell growth
ISO
GO:0030509
BMP signaling pathway
IEA
GO:0030509
BMP signaling pathway
ISO
GO:0030511
positive regulation of transforming growth factor beta receptor signaling pathway
IEA
GO:0030511
positive regulation of transforming growth factor beta receptor signaling pathway
ISO
GO:0032525
somite rostral/caudal axis specification
IEA
GO:0032525
somite rostral/caudal axis specification
ISO
GO:0032909
regulation of transforming growth factor beta2 production
IEA
GO:0032909
regulation of transforming growth factor beta2 production
ISO
GO:0042127
regulation of cell proliferation
ISO
GO:0042177
negative regulation of protein catabolic process
IEA
GO:0042177
negative regulation of protein catabolic process
ISO
GO:0045892
negative regulation of transcription, DNA-dependent
IEA
GO:0045892
negative regulation of transcription, DNA-dependent
ISO
GO:0045893
positive regulation of transcription, DNA-dependent
ISO
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IEA
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
ISO
GO:0048589
developmental growth
IEA
GO:0048589
developmental growth
ISO
GO:0048663
neuron fate commitment
IEA
GO:0048663
neuron fate commitment
ISO
GO:0048729
tissue morphogenesis
IEA
GO:0048729
tissue morphogenesis
ISO
GO:0048733
sebaceous gland development
ISO
GO:0048859
formation of anatomical boundary
IEA
GO:0048859
formation of anatomical boundary
ISO
GO:0051098
regulation of binding
IEA
GO:0051098
regulation of binding
ISO
GO:0051797
regulation of hair follicle development
ISO
GO:0060021
palate development
ISO
GO:0060391
positive regulation of SMAD protein import into nucleus
ISO
GO:0060395
SMAD protein signal transduction
IEA
GO:0060395
SMAD protein signal transduction
ISO
GO:0060548
negative regulation of cell death
ISO
GO:0071559
response to transforming growth factor beta stimulus
IEA
GO:0071559
response to transforming growth factor beta stimulus
ISO
GO:0072133
metanephric mesenchyme morphogenesis
ISO
GO:0072134
nephrogenic mesenchyme morphogenesis
ISO
cellular_component
GO:0005622
intracellular
IEA
GO:0005634
nucleus
IDA
GO:0005634
nucleus
ISO
GO:0005654
nucleoplasm
IEA
GO:0005667
transcription factor complex
ISO
GO:0005730
nucleolus
ISO
GO:0005737
cytoplasm
IDA
GO:0005737
cytoplasm
ISO
GO:0005813
centrosome
IEA
GO:0005813
centrosome
ISO
GO:0005829
cytosol
IEA
GO:0032444
activin responsive factor complex
IEA
GO:0032444
activin responsive factor complex
ISO
GO:0043234
protein complex
IDA
GO:0071141
SMAD protein complex
ISO
molecular_function
GO:0000987
core promoter proximal region sequence-specific DNA binding
ISO
GO:0000988
protein binding transcription factor activity
ISO
GO:0003677
DNA binding
IDA
GO:0003677
DNA binding
ISO
GO:0003682
chromatin binding
IEA
GO:0003682
chromatin binding
ISO
GO:0003700
sequence-specific DNA binding transcription factor activity
IEA
GO:0003700
sequence-specific DNA binding transcription factor activity
ISO
GO:0005515
protein binding
IPI
GO:0005518
collagen binding
IEA
GO:0005518
collagen binding
ISO
GO:0030616
transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
IEA
GO:0030616
transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
ISO
GO:0042802
identical protein binding
ISO
GO:0042803
protein homodimerization activity
IEA
GO:0042803
protein homodimerization activity
ISO
GO:0043565
sequence-specific DNA binding
IEA
GO:0043565
sequence-specific DNA binding
ISO
GO:0044212
transcription regulatory region DNA binding
ISO
GO:0046332
SMAD binding
IPI
GO:0070411
I-SMAD binding
IEA
GO:0070411
I-SMAD binding
ISO
GO:0070412
R-SMAD binding
IEA
GO:0070412
R-SMAD binding
ISO
Protein-protein interaction details for Smad4 (
Rattus norvegicus
)
(Information is obtained from BioGRID)
Not available