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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for MLH1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000239pachyteneIEA
GO:0000289nuclear-transcribed mRNA poly(A) tail shorteningIEA
GO:0000712resolution of meiotic recombination intermediatesIEA
GO:0001666response to hypoxiaIEA
GO:0006200ATP catabolic processIBA
GO:0006298mismatch repairIBA
GO:0006298mismatch repairIEA
GO:0006303double-strand break repair via nonhomologous end joiningIEA
GO:0007049cell cycleIEA
GO:0007060male meiosis chromosome segregationIEA
GO:0007131reciprocal meiotic recombinationIBA
GO:0007283spermatogenesisIEA
GO:0008630DNA damage response, signal transduction resulting in induction of apoptosisIEA
GO:0009636response to toxinIEA
GO:0016446somatic hypermutation of immunoglobulin genesIBA
GO:0016446somatic hypermutation of immunoglobulin genesIEA
GO:0042493response to drugIEA
GO:0043060meiotic metaphase I plate congressionIEA
GO:0045190isotype switchingIEA
GO:0045950negative regulation of mitotic recombinationIEA
GO:0048477oogenesisIEA
GO:0051257spindle midzone assembly involved in meiosisIEA
GO:0071407cellular response to organic cyclic compoundIEA
cellular_component
GO:0000795synaptonemal complexIBA
GO:0000795synaptonemal complexIEA
GO:0001673male germ cell nucleusIEA
GO:0005634nucleusIC
GO:0005634nucleusIEA
GO:0005712chiasmaIBA
GO:0005712chiasmaIEA
GO:0032389MutLalpha complexIBA
GO:0032389MutLalpha complexIEA
GO:0032390MutLbeta complexIBA
molecular_function
GO:0003697single-stranded DNA bindingIDA
GO:0005515protein bindingIPI
GO:0005524ATP bindingIEA
GO:0016887ATPase activityIBA
GO:0030983mismatched DNA bindingIBA
GO:0030983mismatched DNA bindingIEA
GO:0032137guanine/thymine mispair bindingIEA
GO:0032407MutSalpha complex bindingIDA
GO:0043566structure-specific DNA bindingIEA

Protein-protein interaction details for MLH1 (Homo sapiens)
(Information is obtained from BioGRID)
Not available