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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SMAD6 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001657ureteric bud developmentIEA
GO:0006955immune responseIMP
GO:0007179transforming growth factor beta receptor signaling pathwayTAS
GO:0007352zygotic specification of dorsal/ventral axisIMP
GO:0010991negative regulation of SMAD protein complex assemblyIDA
GO:0030509BMP signaling pathwayTAS
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathwayIMP
GO:0030514negative regulation of BMP signaling pathwayIDA
GO:0031589cell-substrate adhesionIMP
GO:0034616response to laminar fluid shear stressIEP
GO:0043066negative regulation of apoptosisIMP
GO:0043154negative regulation of caspase activityIMP
GO:0043627response to estrogen stimulusIEA
GO:0045750positive regulation of S phase of mitotic cell cycleIMP
GO:0060394negative regulation of pathway-restricted SMAD protein phosphorylationIDA
GO:0060394negative regulation of pathway-restricted SMAD protein phosphorylationIMP
cellular_component
GO:0005622intracellularIEA
GO:0005634nucleusIDA
GO:0005667transcription factor complexIEA
GO:0005737cytoplasmTAS
GO:0005829cytosolTAS
molecular_function
GO:0003682chromatin bindingIDA
GO:0003700sequence-specific DNA binding transcription factor activityIEA
GO:0005515protein bindingIPI
GO:0030617transforming growth factor beta receptor, inhibitory cytoplasmic mediator activityIDA
GO:0030617transforming growth factor beta receptor, inhibitory cytoplasmic mediator activityIMP
GO:0031625ubiquitin protein ligase bindingIPI
GO:0034713type I transforming growth factor beta receptor bindingIDA
GO:0044212transcription regulatory region DNA bindingIDA
GO:0070410co-SMAD bindingIPI
GO:0070411I-SMAD bindingIPI
GO:0070412R-SMAD bindingIPI
GO:0070698type I activin receptor bindingIDA

Protein-protein interaction details for SMAD6 (Homo sapiens)
(Information is obtained from BioGRID)
Not available