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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IRS1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0002053 positive regulation of mesenchymal cell proliferation IEA GO:0007165 signal transduction TAS GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway ISS GO:0008284 positive regulation of cell proliferation NAS GO:0008286 insulin receptor signaling pathway IDA GO:0008286 insulin receptor signaling pathway IMP GO:0008286 insulin receptor signaling pathway IPI GO:0008286 insulin receptor signaling pathway TAS GO:0008543 fibroblast growth factor receptor signaling pathway TAS GO:0010468 regulation of gene expression IEA GO:0010907 positive regulation of glucose metabolic process IMP GO:0014065 phosphatidylinositol 3-kinase cascade IDA GO:0016042 lipid catabolic process IEA GO:0030335 positive regulation of cell migration IEA GO:0030879 mammary gland development IEA GO:0032000 positive regulation of fatty acid beta-oxidation IMP GO:0032868 response to insulin stimulus IDA GO:0032869 cellular response to insulin stimulus IMP GO:0034504 protein localization to nucleus IEA GO:0042327 positive regulation of phosphorylation IEA GO:0042593 glucose homeostasis TAS GO:0043434 response to peptide hormone stimulus ISS GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity ISS GO:0045725 positive regulation of glycogen biosynthetic process IMP GO:0045725 positive regulation of glycogen biosynthetic process NAS GO:0046326 positive regulation of glucose import IMP GO:0046627 negative regulation of insulin receptor signaling pathway ISS GO:0046628 positive regulation of insulin receptor signaling pathway ISS GO:0046676 negative regulation of insulin secretion IDA GO:0048009 insulin-like growth factor receptor signaling pathway IPI GO:0048011 nerve growth factor receptor signaling pathway TAS GO:0048015 phosphatidylinositol-mediated signaling TAS GO:0051291 protein heterooligomerization IEA GO:0070094 positive regulation of glucagon secretion IEA GO:0090275 negative regulation of somatostatin secretion IEA cellular_component GO:0005634 nucleus ISS GO:0005737 cytoplasm ISS GO:0005792 microsome ISS GO:0005829 cytosol TAS GO:0005886 plasma membrane TAS GO:0005899 insulin receptor complex ISS GO:0005901 caveola IDA molecular_function GO:0004871 signal transducer activity IEA GO:0005010 insulin-like growth factor-activated receptor activity IEA GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity ISS GO:0005080 protein kinase C binding ISS GO:0005158 insulin receptor binding IPI GO:0005159 insulin-like growth factor receptor binding IPI GO:0005515 protein binding IPI GO:0042169 SH2 domain binding ISS GO:0043548 phosphatidylinositol 3-kinase binding IPI GO:0043548 phosphatidylinositol 3-kinase binding ISS GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS

Protein-protein interaction details for IRS1 (Homo sapiens) (Information is obtained from BioGRID)

Not available