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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IRF3 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IEA GO:0002756 MyD88-independent toll-like receptor signaling pathway TAS GO:0006366 transcription from RNA polymerase II promoter TAS GO:0008063 Toll signaling pathway TAS GO:0009615 response to virus IEA GO:0009617 response to bacterium IEA GO:0019221 cytokine-mediated signaling pathway TAS GO:0031663 lipopolysaccharide-mediated signaling pathway IEA GO:0032480 negative regulation of type I interferon production TAS GO:0032496 response to lipopolysaccharide IEA GO:0034138 toll-like receptor 3 signaling pathway TAS GO:0034142 toll-like receptor 4 signaling pathway TAS GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade IEA GO:0043330 response to exogenous dsRNA IEA GO:0044419 interspecies interaction between organisms IEA GO:0045087 innate immune response TAS GO:0045351 type I interferon biosynthetic process IEA GO:0045358 negative regulation of interferon-beta biosynthetic process IEA GO:0050689 negative regulation of defense response to virus by host IEA GO:0050715 positive regulation of cytokine secretion IEA GO:0060333 interferon-gamma-mediated signaling pathway TAS GO:0060337 type I interferon-mediated signaling pathway TAS GO:0071359 cellular response to dsRNA IEA cellular_component GO:0005634 nucleus IDA GO:0005654 nucleoplasm TAS GO:0005737 cytoplasm IDA GO:0005829 cytosol TAS GO:0005886 plasma membrane TAS GO:0010008 endosome membrane TAS molecular_function GO:0000975 regulatory region DNA binding IEA GO:0003677 DNA binding NAS GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0003712 transcription cofactor activity TAS GO:0005515 protein binding IPI GO:0042802 identical protein binding IPI GO:0042803 protein homodimerization activity IPI GO:0044212 transcription regulatory region DNA binding IEA

Protein-protein interaction details for IRF3 (Homo sapiens) (Information is obtained from BioGRID)

Not available