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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IRAK2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000187 activation of MAPK activity TAS GO:0001959 regulation of cytokine-mediated signaling pathway IMP GO:0002218 activation of innate immune response TAS GO:0002224 toll-like receptor signaling pathway TAS GO:0002755 MyD88-dependent toll-like receptor signaling pathway TAS GO:0002756 MyD88-independent toll-like receptor signaling pathway TAS GO:0006468 protein phosphorylation TAS GO:0006954 inflammatory response TAS GO:0007165 signal transduction IEA GO:0007249 I-kappaB kinase/NF-kappaB cascade TAS GO:0007254 JNK cascade TAS GO:0008063 Toll signaling pathway TAS GO:0031663 lipopolysaccharide-mediated signaling pathway IEA GO:0032088 negative regulation of NF-kappaB transcription factor activity IMP GO:0034130 toll-like receptor 1 signaling pathway TAS GO:0034134 toll-like receptor 2 signaling pathway TAS GO:0034138 toll-like receptor 3 signaling pathway TAS GO:0034142 toll-like receptor 4 signaling pathway TAS GO:0045087 innate immune response TAS GO:0051092 positive regulation of NF-kappaB transcription factor activity IMP GO:0051092 positive regulation of NF-kappaB transcription factor activity TAS GO:0051403 stress-activated MAPK cascade TAS GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway TAS GO:0070498 interleukin-1-mediated signaling pathway IMP GO:0070555 response to interleukin-1 IMP cellular_component GO:0005829 cytosol TAS GO:0005886 plasma membrane TAS GO:0009986 cell surface IDA GO:0010008 endosome membrane TAS molecular_function GO:0000166 nucleotide binding IEA GO:0004672 protein kinase activity IEA GO:0004704 NF-kappaB-inducing kinase activity TAS GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0016772 transferase activity, transferring phosphorus-containing groups IEA GO:0042803 protein homodimerization activity IPI GO:0046982 protein heterodimerization activity IPI

Protein-protein interaction details for IRAK2 (Homo sapiens) (Information is obtained from BioGRID)

Not available