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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IRAK1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000187 activation of MAPK activity TAS GO:0001959 regulation of cytokine-mediated signaling pathway IMP GO:0002218 activation of innate immune response TAS GO:0002224 toll-like receptor signaling pathway TAS GO:0002755 MyD88-dependent toll-like receptor signaling pathway TAS GO:0002756 MyD88-independent toll-like receptor signaling pathway TAS GO:0006468 protein phosphorylation TAS GO:0006916 anti-apoptosis TAS GO:0007165 signal transduction IEA GO:0007165 signal transduction NAS GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway NAS GO:0007250 activation of NF-kappaB-inducing kinase activity IDA GO:0007254 JNK cascade TAS GO:0008063 Toll signaling pathway TAS GO:0016567 protein ubiquitination TAS GO:0031663 lipopolysaccharide-mediated signaling pathway IMP GO:0032088 negative regulation of NF-kappaB transcription factor activity IMP GO:0032494 response to peptidoglycan IEA GO:0032496 response to lipopolysaccharide IMP GO:0034130 toll-like receptor 1 signaling pathway TAS GO:0034134 toll-like receptor 2 signaling pathway IMP GO:0034134 toll-like receptor 2 signaling pathway TAS GO:0034138 toll-like receptor 3 signaling pathway TAS GO:0034142 toll-like receptor 4 signaling pathway TAS GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade TAS GO:0043507 positive regulation of JUN kinase activity IEA GO:0045087 innate immune response TAS GO:0045892 negative regulation of transcription, DNA-dependent IEA GO:0045893 positive regulation of transcription, DNA-dependent NAS GO:0046777 protein autophosphorylation IDA GO:0046777 protein autophosphorylation NAS GO:0048011 nerve growth factor receptor signaling pathway TAS GO:0051092 positive regulation of NF-kappaB transcription factor activity IDA GO:0051092 positive regulation of NF-kappaB transcription factor activity TAS GO:0051259 protein oligomerization IMP GO:0051403 stress-activated MAPK cascade TAS GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway TAS GO:0070498 interleukin-1-mediated signaling pathway IMP GO:0070555 response to interleukin-1 IMP GO:0090370 negative regulation of cholesterol efflux IEA cellular_component GO:0005624 membrane fraction IEA GO:0005634 nucleus IEA GO:0005737 cytoplasm IEA GO:0005829 cytosol TAS GO:0005886 plasma membrane TAS GO:0010008 endosome membrane TAS GO:0045323 interleukin-1 receptor complex NAS molecular_function GO:0000166 nucleotide binding IEA GO:0004672 protein kinase activity IDA GO:0004672 protein kinase activity TAS GO:0004674 protein serine/threonine kinase activity EXP GO:0004674 protein serine/threonine kinase activity IEA GO:0004674 protein serine/threonine kinase activity NAS GO:0004704 NF-kappaB-inducing kinase activity TAS GO:0004842 ubiquitin-protein ligase activity TAS GO:0004872 receptor activity IEA GO:0005149 interleukin-1 receptor binding IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0016301 kinase activity IDA GO:0016772 transferase activity, transferring phosphorus-containing groups IEA GO:0042803 protein homodimerization activity IPI GO:0042803 protein homodimerization activity NAS GO:0046982 protein heterodimerization activity IPI

Protein-protein interaction details for IRAK1 (Homo sapiens) (Information is obtained from BioGRID)

Not available