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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IRF8 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000122negative regulation of transcription from RNA polymerase II promoterTAS
GO:0006909phagocytosisIEA
GO:0006955immune responseIEA
GO:0019221cytokine-mediated signaling pathwayTAS
GO:0030099myeloid cell differentiationIEA
GO:0032729positive regulation of interferon-gamma productionIEA
GO:0032735positive regulation of interleukin-12 productionIEA
GO:0042742defense response to bacteriumIEA
GO:0042832defense response to protozoanIEA
GO:0044130negative regulation of growth of symbiont in hostIEA
GO:0045893positive regulation of transcription, DNA-dependentIEA
GO:0060333interferon-gamma-mediated signaling pathwayTAS
GO:0060337type I interferon-mediated signaling pathwayTAS
GO:0071222cellular response to lipopolysaccharideIEA
cellular_component
GO:0005634nucleusIEA
GO:0005829cytosolTAS
molecular_function
GO:0000975regulatory region DNA bindingIEA
GO:0003700sequence-specific DNA binding transcription factor activityIEA
GO:0003705sequence-specific distal enhancer binding RNA polymerase II transcription factor activityTAS

Protein-protein interaction details for IRF8 (Homo sapiens)
(Information is obtained from BioGRID)
Not available