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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Nod2 (Rattus norvegicus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0002227innate immune response in mucosaISO
GO:0002253activation of immune responseISO
GO:0002282microglial cell activation involved in immune responseIDA
GO:0002367cytokine production involved in immune responseISO
GO:0002381immunoglobulin production involved in immunoglobulin mediated immune responseISO
GO:0002606positive regulation of dendritic cell antigen processing and presentationISO
GO:0002710negative regulation of T cell mediated immunityISO
GO:0002732positive regulation of dendritic cell cytokine productionIDA
GO:0002830positive regulation of type 2 immune responseISO
GO:0002862negative regulation of inflammatory response to antigenic stimulusISO
GO:0002925positive regulation of humoral immune response mediated by circulating immunoglobulinISO
GO:0006965positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteriaIEA
GO:0006965positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteriaISO
GO:0007584response to nutrientIEP
GO:0008284positive regulation of cell proliferationIDA
GO:0016045detection of bacteriumIEA
GO:0016045detection of bacteriumISO
GO:0031398positive regulation of protein ubiquitinationISO
GO:0032088negative regulation of NF-kappaB transcription factor activityIEA
GO:0032088negative regulation of NF-kappaB transcription factor activityISO
GO:0032494response to peptidoglycanISO
GO:0032495response to muramyl dipeptideIDA
GO:0032495response to muramyl dipeptideISO
GO:0032496response to lipopolysaccharideIEA
GO:0032496response to lipopolysaccharideISO
GO:0032498detection of muramyl dipeptideIEA
GO:0032498detection of muramyl dipeptideISO
GO:0032689negative regulation of interferon-gamma productionIEA
GO:0032689negative regulation of interferon-gamma productionISO
GO:0032695negative regulation of interleukin-12 productionIEA
GO:0032695negative regulation of interleukin-12 productionISO
GO:0032701negative regulation of interleukin-18 productionIEA
GO:0032701negative regulation of interleukin-18 productionISO
GO:0032703negative regulation of interleukin-2 productionIEA
GO:0032703negative regulation of interleukin-2 productionISO
GO:0032720negative regulation of tumor necrosis factor productionIEA
GO:0032720negative regulation of tumor necrosis factor productionISO
GO:0032731positive regulation of interleukin-1 beta productionISO
GO:0032733positive regulation of interleukin-10 productionISO
GO:0032735positive regulation of interleukin-12 productionIEA
GO:0032735positive regulation of interleukin-12 productionISO
GO:0032740positive regulation of interleukin-17 productionIEA
GO:0032740positive regulation of interleukin-17 productionISO
GO:0032755positive regulation of interleukin-6 productionIEA
GO:0032755positive regulation of interleukin-6 productionISO
GO:0032760positive regulation of tumor necrosis factor productionIEA
GO:0032760positive regulation of tumor necrosis factor productionISO
GO:0032874positive regulation of stress-activated MAPK cascadeIEA
GO:0032874positive regulation of stress-activated MAPK cascadeISO
GO:0034136negative regulation of toll-like receptor 2 signaling pathwayIEA
GO:0034136negative regulation of toll-like receptor 2 signaling pathwayISO
GO:0035419activation of MAPK activity involved in innate immune responseISO
GO:0035556intracellular signal transductionIEA
GO:0035556intracellular signal transductionISO
GO:0042742defense response to bacteriumIDA
GO:0042742defense response to bacteriumISO
GO:0042981regulation of apoptosisIEA
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cascadeIEA
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cascadeISO
GO:0043330response to exogenous dsRNAIEA
GO:0043330response to exogenous dsRNAISO
GO:0043410positive regulation of MAPKKK cascadeISO
GO:0043552positive regulation of phosphatidylinositol 3-kinase activityISO
GO:0044130negative regulation of growth of symbiont in hostIEA
GO:0044130negative regulation of growth of symbiont in hostISO
GO:0045089positive regulation of innate immune responseIEA
GO:0045089positive regulation of innate immune responseISO
GO:0045747positive regulation of Notch signaling pathwayISO
GO:0046330positive regulation of JNK cascadeIEA
GO:0046330positive regulation of JNK cascadeISO
GO:0050679positive regulation of epithelial cell proliferationISO
GO:0050718positive regulation of interleukin-1 beta secretionIEA
GO:0050718positive regulation of interleukin-1 beta secretionISO
GO:0050731positive regulation of peptidyl-tyrosine phosphorylationIEA
GO:0050731positive regulation of peptidyl-tyrosine phosphorylationISO
GO:0050766positive regulation of phagocytosisIEA
GO:0050766positive regulation of phagocytosisISO
GO:0050830defense response to Gram-positive bacteriumIEA
GO:0050830defense response to Gram-positive bacteriumISO
GO:0050871positive regulation of B cell activationIEA
GO:0050871positive regulation of B cell activationISO
GO:0051092positive regulation of NF-kappaB transcription factor activityIEA
GO:0051092positive regulation of NF-kappaB transcription factor activityISO
GO:0051353positive regulation of oxidoreductase activityISO
GO:0051770positive regulation of nitric-oxide synthase biosynthetic processISO
GO:0052033pathogen-associated molecular pattern dependent induction by symbiont of host innate immunityIDA
GO:0060585positive regulation of prostaglandin-endoperoxide synthase activityISO
GO:0070374positive regulation of ERK1 and ERK2 cascadeIEA
GO:0070374positive regulation of ERK1 and ERK2 cascadeISO
GO:0070431nucleotide-binding oligomerization domain containing 2 signaling pathwayIEA
GO:0070431nucleotide-binding oligomerization domain containing 2 signaling pathwayISO
GO:0071224cellular response to peptidoglycanIEA
GO:0071224cellular response to peptidoglycanISO
GO:0071608macrophage inflammatory protein-1 alpha productionIEA
GO:0071608macrophage inflammatory protein-1 alpha productionISO
GO:0090022regulation of neutrophil chemotaxisIEA
GO:0090022regulation of neutrophil chemotaxisISO
GO:2000110negative regulation of macrophage apoptosisISO
GO:2000363positive regulation of prostaglandin-E synthase activityISO
cellular_component
GO:0005622intracellularIEA
GO:0005829cytosolISO
GO:0005886plasma membraneISO
GO:0008180signalosomeIEA
GO:0008180signalosomeISO
GO:0009986cell surfaceIEA
GO:0009986cell surfaceISO
GO:0031982vesicleIEA
GO:0031982vesicleISO
GO:0042995cell projectionIDA
molecular_function
GO:0000166nucleotide bindingIEA
GO:0005524ATP bindingIEA
GO:0019899enzyme bindingIEA
GO:0019899enzyme bindingISO
GO:0019901protein kinase bindingIEA
GO:0019901protein kinase bindingISO
GO:0032500muramyl dipeptide bindingIDA
GO:0032500muramyl dipeptide bindingIEA
GO:0032500muramyl dipeptide bindingISO
GO:0042834peptidoglycan bindingISO
GO:0050700CARD domain bindingIEA
GO:0050700CARD domain bindingISO

Protein-protein interaction details for Nod2 (Rattus norvegicus)
(Information is obtained from BioGRID)
Not available