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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TBK1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0002218activation of innate immune responseIEA
GO:0002756MyD88-independent toll-like receptor signaling pathwayTAS
GO:0006468protein phosphorylationNAS
GO:0006954inflammatory responseTAS
GO:0007249I-kappaB kinase/NF-kappaB cascadeTAS
GO:0008063Toll signaling pathwayTAS
GO:0009615response to virusTAS
GO:0010629negative regulation of gene expressionIEA
GO:0032480negative regulation of type I interferon productionTAS
GO:0032606type I interferon productionTAS
GO:0032727positive regulation of interferon-alpha productionIDA
GO:0032728positive regulation of interferon-beta productionIDA
GO:0034138toll-like receptor 3 signaling pathwayTAS
GO:0034142toll-like receptor 4 signaling pathwayTAS
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cascadeIEP
GO:0044419interspecies interaction between organismsIEA
GO:0045087innate immune responseTAS
GO:0045359positive regulation of interferon-beta biosynthetic processIEA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0050830defense response to Gram-positive bacteriumIEA
cellular_component
GO:0005737cytoplasmIEA
GO:0005829cytosolTAS
GO:0005886plasma membraneTAS
GO:0010008endosome membraneTAS
molecular_function
GO:0000166nucleotide bindingIEA
GO:0003676nucleic acid bindingIEA
GO:0004672protein kinase activityIEA
GO:0004672protein kinase activityNAS
GO:0004674protein serine/threonine kinase activityTAS
GO:0005515protein bindingIPI
GO:0005524ATP bindingIEA
GO:0016772transferase activity, transferring phosphorus-containing groupsIEA
GO:0051219phosphoprotein bindingIPI

Protein-protein interaction details for TBK1 (Homo sapiens)
(Information is obtained from BioGRID)
Not available