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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for GCLC (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006534cysteine metabolic processIDA
GO:0006536glutamate metabolic processIDA
GO:0006750glutathione biosynthetic processIDA
GO:0006750glutathione biosynthetic processIEA
GO:0006750glutathione biosynthetic processIMP
GO:0006750glutathione biosynthetic processTAS
GO:0006805xenobiotic metabolic processTAS
GO:0006916anti-apoptosisIDA
GO:0006979response to oxidative stressIDA
GO:0009408response to heatIDA
GO:0009410response to xenobiotic stimulusIEA
GO:0009725response to hormone stimulusIDA
GO:0019852L-ascorbic acid metabolic processIEA
GO:0031397negative regulation of protein ubiquitinationIEA
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic processIEA
GO:0043524negative regulation of neuron apoptosisIEA
GO:0045454cell redox homeostasisIDA
GO:0045892negative regulation of transcription, DNA-dependentIDA
GO:0046685response to arsenic-containing substanceIEA
GO:0050880regulation of blood vessel sizeIMP
GO:0051409response to nitrosative stressIEA
GO:0051900regulation of mitochondrial depolarizationIEA
cellular_component
GO:0005737cytoplasmIBA
GO:0005829cytosolIEA
GO:0005829cytosolTAS
GO:0017109glutamate-cysteine ligase complexIEA
molecular_function
GO:0000166nucleotide bindingIEA
GO:0000287magnesium ion bindingIDA
GO:0004357glutamate-cysteine ligase activityIDA
GO:0004357glutamate-cysteine ligase activityIEA
GO:0004357glutamate-cysteine ligase activityIMP
GO:0005524ATP bindingIEA
GO:0016595glutamate bindingIDA
GO:0016874ligase activityIEA
GO:0043531ADP bindingIDA
GO:0046982protein heterodimerization activityIEA
GO:0050662coenzyme bindingIPI

Protein-protein interaction details for GCLC (Homo sapiens)
(Information is obtained from BioGRID)
Not available