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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PTPN22 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006470protein dephosphorylationIDA
GO:0006470protein dephosphorylationTAS
GO:0030217T cell differentiationIEA
GO:0030217T cell differentiationISS
GO:0032817regulation of natural killer cell proliferationIDA
GO:0035335peptidyl-tyrosine dephosphorylationIDA
GO:0035644phosphoanandamide dephosphorylationIEA
GO:0035644phosphoanandamide dephosphorylationISS
GO:0045088regulation of innate immune responseIC
GO:0050852T cell receptor signaling pathwayIEA
GO:0050855regulation of B cell receptor signaling pathwayNAS
GO:0050860negative regulation of T cell receptor signaling pathwayIDA
GO:0050868negative regulation of T cell activationIEA
GO:0050868negative regulation of T cell activationIMP
cellular_component
GO:0005634nucleusIDA
GO:0005634nucleusIEA
GO:0005737cytoplasmIDA
GO:0005737cytoplasmIEA
GO:0005737cytoplasmTAS
GO:0009898internal side of plasma membraneIDA
GO:0009898internal side of plasma membraneIEA
GO:0048471perinuclear region of cytoplasmIDA
molecular_function
GO:0004725protein tyrosine phosphatase activityIDA
GO:0004725protein tyrosine phosphatase activityIEA
GO:0005515protein bindingIPI
GO:0016787hydrolase activityIEA
GO:0016791phosphatase activityIEA
GO:0017124SH3 domain bindingIEA
GO:0017124SH3 domain bindingISS
GO:0019900kinase bindingIEA
GO:0019900kinase bindingISS

Protein-protein interaction details for PTPN22 (Homo sapiens)
(Information is obtained from BioGRID)
Not available