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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Nod2 (Mus musculus) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0002227 innate immune response in mucosa IMP GO:0002253 activation of immune response IMP GO:0002282 microglial cell activation involved in immune response ISO GO:0002367 cytokine production involved in immune response ISO GO:0002381 immunoglobulin production involved in immunoglobulin mediated immune response IMP GO:0002606 positive regulation of dendritic cell antigen processing and presentation IMP GO:0002710 negative regulation of T cell mediated immunity IMP GO:0002732 positive regulation of dendritic cell cytokine production ISO GO:0002830 positive regulation of type 2 immune response ISO GO:0002862 negative regulation of inflammatory response to antigenic stimulus IMP GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin IMP GO:0006952 defense response TAS GO:0006954 inflammatory response TAS GO:0006965 positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria IMP GO:0007165 signal transduction TAS GO:0008284 positive regulation of cell proliferation ISO GO:0009595 detection of biotic stimulus TAS GO:0016045 detection of bacterium ISO GO:0031398 positive regulation of protein ubiquitination IDA GO:0032088 negative regulation of NF-kappaB transcription factor activity IMP GO:0032494 response to peptidoglycan IDA GO:0032494 response to peptidoglycan IMP GO:0032495 response to muramyl dipeptide IDA GO:0032495 response to muramyl dipeptide IMP GO:0032495 response to muramyl dipeptide ISO GO:0032496 response to lipopolysaccharide IMP GO:0032498 detection of muramyl dipeptide ISO GO:0032689 negative regulation of interferon-gamma production IMP GO:0032695 negative regulation of interleukin-12 production IDA GO:0032695 negative regulation of interleukin-12 production IMP GO:0032701 negative regulation of interleukin-18 production IMP GO:0032703 negative regulation of interleukin-2 production IMP GO:0032720 negative regulation of tumor necrosis factor production IMP GO:0032731 positive regulation of interleukin-1 beta production ISO GO:0032733 positive regulation of interleukin-10 production IMP GO:0032735 positive regulation of interleukin-12 production IDA GO:0032735 positive regulation of interleukin-12 production IMP GO:0032740 positive regulation of interleukin-17 production ISO GO:0032755 positive regulation of interleukin-6 production IDA GO:0032755 positive regulation of interleukin-6 production IGI GO:0032755 positive regulation of interleukin-6 production IMP GO:0032755 positive regulation of interleukin-6 production ISO GO:0032760 positive regulation of tumor necrosis factor production IDA GO:0032760 positive regulation of tumor necrosis factor production IGI GO:0032760 positive regulation of tumor necrosis factor production IMP GO:0032760 positive regulation of tumor necrosis factor production ISO GO:0032874 positive regulation of stress-activated MAPK cascade IDA GO:0032874 positive regulation of stress-activated MAPK cascade ISO GO:0034136 negative regulation of toll-like receptor 2 signaling pathway IMP GO:0035419 activation of MAPK activity involved in innate immune response IDA GO:0035556 intracellular signal transduction ISO GO:0042742 defense response to bacterium ISO GO:0042981 regulation of apoptosis IEA GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade IDA GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade ISO GO:0043330 response to exogenous dsRNA IMP GO:0043410 positive regulation of MAPKKK cascade IMP GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity IMP GO:0044130 negative regulation of growth of symbiont in host IMP GO:0045089 positive regulation of innate immune response IMP GO:0045747 positive regulation of Notch signaling pathway IDA GO:0046330 positive regulation of JNK cascade IDA GO:0046330 positive regulation of JNK cascade ISO GO:0050679 positive regulation of epithelial cell proliferation IMP GO:0050718 positive regulation of interleukin-1 beta secretion IDA GO:0050718 positive regulation of interleukin-1 beta secretion ISO GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IMP GO:0050766 positive regulation of phagocytosis IMP GO:0050830 defense response to Gram-positive bacterium IGI GO:0050830 defense response to Gram-positive bacterium IMP GO:0050871 positive regulation of B cell activation ISO GO:0051092 positive regulation of NF-kappaB transcription factor activity IMP GO:0051092 positive regulation of NF-kappaB transcription factor activity ISO GO:0051259 protein oligomerization TAS GO:0051353 positive regulation of oxidoreductase activity IDA GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process IMP GO:0052033 pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity ISO GO:0060585 positive regulation of prostaglandin-endoperoxide synthase activity IDA GO:0070374 positive regulation of ERK1 and ERK2 cascade IDA GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway ISO GO:0071224 cellular response to peptidoglycan IMP GO:0071608 macrophage inflammatory protein-1 alpha production IMP GO:0090022 regulation of neutrophil chemotaxis IMP GO:2000110 negative regulation of macrophage apoptosis IDA GO:2000363 positive regulation of prostaglandin-E synthase activity IDA cellular_component GO:0005622 intracellular IEA GO:0005737 cytoplasm TAS GO:0005829 cytosol ISO GO:0005886 plasma membrane ISO GO:0009986 cell surface ISO GO:0031982 vesicle ISO GO:0042995 cell projection ISO molecular_function GO:0000166 nucleotide binding IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters IEA GO:0019899 enzyme binding ISO GO:0019901 protein kinase binding ISO GO:0032500 muramyl dipeptide binding ISO GO:0042834 peptidoglycan binding ISO GO:0042834 peptidoglycan binding TAS GO:0050700 CARD domain binding ISO

Protein-protein interaction details for Nod2 (Mus musculus) (Information is obtained from BioGRID)

Not available