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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for Cdkn2a (
Rattus norvegicus
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000075
cell cycle checkpoint
ISO
GO:0000079
regulation of cyclin-dependent protein kinase activity
ISO
GO:0000082
G1/S transition of mitotic cell cycle
ISO
GO:0000209
protein polyubiquitination
ISO
GO:0000209
protein polyubiquitination
ISS
GO:0001953
negative regulation of cell-matrix adhesion
ISO
GO:0006309
DNA fragmentation involved in apoptotic nuclear change
ISO
GO:0006355
regulation of transcription, DNA-dependent
IEA
GO:0006355
regulation of transcription, DNA-dependent
ISO
GO:0006364
rRNA processing
IEA
GO:0006469
negative regulation of protein kinase activity
ISO
GO:0006915
apoptosis
IEA
GO:0006917
induction of apoptosis
ISO
GO:0006919
activation of caspase activity
ISO
GO:0007049
cell cycle
IEA
GO:0007050
cell cycle arrest
ISO
GO:0007265
Ras protein signal transduction
ISO
GO:0007568
aging
IEP
GO:0007568
aging
ISO
GO:0007569
cell aging
ISO
GO:0008285
negative regulation of cell proliferation
ISO
GO:0008544
epidermis development
ISO
GO:0008637
apoptotic mitochondrial changes
ISO
GO:0009303
rRNA transcription
ISO
GO:0010033
response to organic substance
IEP
GO:0010243
response to organic nitrogen
IDA
GO:0010389
regulation of G2/M transition of mitotic cell cycle
ISO
GO:0010468
regulation of gene expression
ISO
GO:0014070
response to organic cyclic compound
IDA
GO:0030308
negative regulation of cell growth
ISO
GO:0030889
negative regulation of B cell proliferation
ISO
GO:0031647
regulation of protein stability
ISO
GO:0031648
protein destabilization
ISO
GO:0032088
negative regulation of NF-kappaB transcription factor activity
ISO
GO:0033088
negative regulation of immature T cell proliferation in thymus
ISO
GO:0033235
positive regulation of protein sumoylation
ISO
GO:0033600
negative regulation of mammary gland epithelial cell proliferation
ISO
GO:0034393
positive regulation of smooth muscle cell apoptosis
ISO
GO:0035019
somatic stem cell maintenance
ISO
GO:0035986
senescence-associated heterochromatin focus formation
ISO
GO:0042326
negative regulation of phosphorylation
ISO
GO:0042493
response to drug
IDA
GO:0042493
response to drug
IEP
GO:0043517
positive regulation of DNA damage response, signal transduction by p53 class mediator
ISO
GO:0045736
negative regulation of cyclin-dependent protein kinase activity
ISO
GO:0045786
negative regulation of cell cycle
ISO
GO:0045786
negative regulation of cell cycle
TAS
GO:0045892
negative regulation of transcription, DNA-dependent
ISO
GO:0045893
positive regulation of transcription, DNA-dependent
ISO
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
ISO
GO:0046822
regulation of nucleocytoplasmic transport
ISO
GO:0046825
regulation of protein export from nucleus
ISO
GO:0048103
somatic stem cell division
ISO
GO:0050821
protein stabilization
ISO
GO:0051091
positive regulation of sequence-specific DNA binding transcription factor activity
ISO
GO:0051444
negative regulation of ubiquitin-protein ligase activity
ISO
GO:0060058
positive regulation of apoptosis involved in mammary gland involution
ISO
GO:0070534
protein K63-linked ubiquitination
ISO
GO:0070534
protein K63-linked ubiquitination
ISS
GO:0071158
positive regulation of cell cycle arrest
ISO
GO:0090398
cellular senescence
ISO
GO:0090399
replicative senescence
ISO
GO:2000111
positive regulation of macrophage apoptosis
ISO
GO:2000774
positive regulation of cellular senescence
ISO
cellular_component
GO:0001652
granular component
ISO
GO:0005634
nucleus
IDA
GO:0005634
nucleus
ISO
GO:0005634
nucleus
NAS
GO:0005654
nucleoplasm
ISO
GO:0005654
nucleoplasm
ISS
GO:0005730
nucleolus
ISO
GO:0005730
nucleolus
ISS
GO:0005737
cytoplasm
ISO
GO:0016604
nuclear body
ISO
GO:0035985
senescence-associated heterochromatin focus
ISO
GO:0043234
protein complex
ISO
molecular_function
GO:0002039
p53 binding
ISO
GO:0003677
DNA binding
IEA
GO:0003700
sequence-specific DNA binding transcription factor activity
ISO
GO:0004861
cyclin-dependent protein kinase inhibitor activity
ISO
GO:0004861
cyclin-dependent protein kinase inhibitor activity
TAS
GO:0008134
transcription factor binding
ISO
GO:0019901
protein kinase binding
ISO
GO:0051059
NF-kappaB binding
ISO
GO:0055105
ubiquitin-protein ligase inhibitor activity
ISO
GO:0070215
MDM2 binding
ISO
Protein-protein interaction details for Cdkn2a (
Rattus norvegicus
)
(Information is obtained from BioGRID)
Not available