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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Tnf (Rattus norvegicus) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000060 protein import into nucleus, translocation IEA GO:0000060 protein import into nucleus, translocation ISO GO:0000122 negative regulation of transcription from RNA polymerase II promoter IEA GO:0000122 negative regulation of transcription from RNA polymerase II promoter ISO GO:0000185 activation of MAPKKK activity IEA GO:0000185 activation of MAPKKK activity ISO GO:0000187 activation of MAPK activity IEA GO:0000187 activation of MAPK activity ISO GO:0001666 response to hypoxia IEP GO:0001775 cell activation IDA GO:0001819 positive regulation of cytokine production ISO GO:0001932 regulation of protein phosphorylation ISO GO:0001934 positive regulation of protein phosphorylation ISO GO:0002037 negative regulation of L-glutamate transport IDA GO:0002439 chronic inflammatory response to antigenic stimulus ISO GO:0002740 negative regulation of cytokine secretion involved in immune response IEA GO:0002740 negative regulation of cytokine secretion involved in immune response ISO GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus IEA GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus ISO GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin IEA GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin ISO GO:0003009 skeletal muscle contraction IEP GO:0006006 glucose metabolic process IEA GO:0006006 glucose metabolic process ISO GO:0006915 apoptosis IDA GO:0006915 apoptosis ISO GO:0006916 anti-apoptosis IEA GO:0006916 anti-apoptosis ISO GO:0006917 induction of apoptosis IDA GO:0006917 induction of apoptosis ISO GO:0006919 activation of caspase activity IEA GO:0006919 activation of caspase activity ISO GO:0006927 transformed cell apoptosis IEA GO:0006927 transformed cell apoptosis ISO GO:0006952 defense response ISO GO:0006954 inflammatory response ISO GO:0006954 inflammatory response TAS GO:0006959 humoral immune response IEA GO:0006959 humoral immune response ISO GO:0007165 signal transduction IDA GO:0007254 JNK cascade ISO GO:0007275 multicellular organismal development IEA GO:0007275 multicellular organismal development ISO GO:0008285 negative regulation of cell proliferation IDA GO:0008624 induction of apoptosis by extracellular signals ISO GO:0008625 induction of apoptosis via death domain receptors IEA GO:0008625 induction of apoptosis via death domain receptors ISO GO:0009612 response to mechanical stimulus IEP GO:0009615 response to virus IEA GO:0009615 response to virus ISO GO:0009887 organ morphogenesis IEA GO:0009887 organ morphogenesis ISO GO:0014823 response to activity IEP GO:0019722 calcium-mediated signaling IDA GO:0030198 extracellular matrix organization IEA GO:0030198 extracellular matrix organization ISO GO:0030316 osteoclast differentiation ISO GO:0030730 sequestering of triglyceride IEA GO:0030730 sequestering of triglyceride ISO GO:0031334 positive regulation of protein complex assembly ISO GO:0031622 positive regulation of fever generation IEA GO:0031622 positive regulation of fever generation ISO GO:0032715 negative regulation of interleukin-6 production IEA GO:0032715 negative regulation of interleukin-6 production ISO GO:0032722 positive regulation of chemokine production IEA GO:0032722 positive regulation of chemokine production ISO GO:0032729 positive regulation of interferon-gamma production IEA GO:0032729 positive regulation of interferon-gamma production ISO GO:0032741 positive regulation of interleukin-18 production IMP GO:0032755 positive regulation of interleukin-6 production IEA GO:0032755 positive regulation of interleukin-6 production ISO GO:0032800 receptor biosynthetic process IEA GO:0032800 receptor biosynthetic process ISO GO:0033138 positive regulation of peptidyl-serine phosphorylation IEA GO:0033138 positive regulation of peptidyl-serine phosphorylation ISO GO:0033209 tumor necrosis factor-mediated signaling pathway IEA GO:0033209 tumor necrosis factor-mediated signaling pathway ISO GO:0034116 positive regulation of heterotypic cell-cell adhesion IEA GO:0034116 positive regulation of heterotypic cell-cell adhesion ISO GO:0042127 regulation of cell proliferation ISO GO:0042346 positive regulation of NF-kappaB import into nucleus IEA GO:0042346 positive regulation of NF-kappaB import into nucleus ISO GO:0042493 response to drug IEP GO:0042742 defense response to bacterium ISO GO:0043065 positive regulation of apoptosis IMP GO:0043066 negative regulation of apoptosis ISO GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade ISO GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade IGI GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade ISO GO:0043243 positive regulation of protein complex disassembly IEA GO:0043243 positive regulation of protein complex disassembly ISO GO:0043406 positive regulation of MAP kinase activity ISO GO:0043525 positive regulation of neuron apoptosis IMP GO:0044130 negative regulation of growth of symbiont in host IEA GO:0044130 negative regulation of growth of symbiont in host ISO GO:0045071 negative regulation of viral genome replication IEA GO:0045071 negative regulation of viral genome replication ISO GO:0045080 positive regulation of chemokine biosynthetic process IEA GO:0045080 positive regulation of chemokine biosynthetic process ISO GO:0045123 cellular extravasation ISO GO:0045429 positive regulation of nitric oxide biosynthetic process IEA GO:0045429 positive regulation of nitric oxide biosynthetic process ISO GO:0045670 regulation of osteoclast differentiation ISO GO:0045672 positive regulation of osteoclast differentiation IEA GO:0045672 positive regulation of osteoclast differentiation ISO GO:0045840 positive regulation of mitosis IMP GO:0045892 negative regulation of transcription, DNA-dependent ISO GO:0045893 positive regulation of transcription, DNA-dependent ISO GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter ISO GO:0045994 positive regulation of translational initiation by iron IEA GO:0045994 positive regulation of translational initiation by iron ISO GO:0046325 negative regulation of glucose import IDA GO:0046325 negative regulation of glucose import ISO GO:0046330 positive regulation of JNK cascade IEA GO:0046330 positive regulation of JNK cascade ISO GO:0048566 embryonic digestive tract development IEA GO:0048566 embryonic digestive tract development ISO GO:0048661 positive regulation of smooth muscle cell proliferation IEA GO:0048661 positive regulation of smooth muscle cell proliferation ISO GO:0050708 regulation of protein secretion ISO GO:0050715 positive regulation of cytokine secretion IEA GO:0050715 positive regulation of cytokine secretion ISO GO:0050729 positive regulation of inflammatory response IMP GO:0050796 regulation of insulin secretion IEA GO:0050796 regulation of insulin secretion ISO GO:0050806 positive regulation of synaptic transmission IMP GO:0050830 defense response to Gram-positive bacterium IEA GO:0050830 defense response to Gram-positive bacterium ISO GO:0050900 leukocyte migration ISO GO:0050901 leukocyte tethering or rolling IEA GO:0050901 leukocyte tethering or rolling ISO GO:0050995 negative regulation of lipid catabolic process IEA GO:0050995 negative regulation of lipid catabolic process ISO GO:0051023 regulation of immunoglobulin secretion IEA GO:0051023 regulation of immunoglobulin secretion ISO GO:0051044 positive regulation of membrane protein ectodomain proteolysis IEA GO:0051044 positive regulation of membrane protein ectodomain proteolysis ISO GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity ISO GO:0051092 positive regulation of NF-kappaB transcription factor activity IEA GO:0051092 positive regulation of NF-kappaB transcription factor activity ISO GO:0051222 positive regulation of protein transport IDA GO:0051222 positive regulation of protein transport ISO GO:0051384 response to glucocorticoid stimulus IEA GO:0051384 response to glucocorticoid stimulus ISO GO:0051533 positive regulation of NFAT protein import into nucleus IEA GO:0051533 positive regulation of NFAT protein import into nucleus ISO GO:0051798 positive regulation of hair follicle development IEA GO:0051798 positive regulation of hair follicle development ISO GO:0051897 positive regulation of protein kinase B signaling cascade ISO GO:0060555 induction of necroptosis by extracellular signals IEA GO:0060555 induction of necroptosis by extracellular signals ISO GO:0060557 positive regulation of vitamin D biosynthetic process IEA GO:0060557 positive regulation of vitamin D biosynthetic process ISO GO:0060559 positive regulation of calcidiol 1-monooxygenase activity IEA GO:0060559 positive regulation of calcidiol 1-monooxygenase activity ISO GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis IEA GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis ISO GO:0060693 regulation of branching involved in salivary gland morphogenesis IEA GO:0060693 regulation of branching involved in salivary gland morphogenesis ISO GO:0061048 negative regulation of branching involved in lung morphogenesis IEA GO:0061048 negative regulation of branching involved in lung morphogenesis ISO GO:0070265 necrotic cell death IEA GO:0070265 necrotic cell death ISO GO:0071230 cellular response to amino acid stimulus ISO GO:0071316 cellular response to nicotine IEA GO:0071316 cellular response to nicotine ISO GO:0071803 positive regulation of podosome assembly IEA GO:0071803 positive regulation of podosome assembly ISO cellular_component GO:0001891 phagocytic cup IEA GO:0001891 phagocytic cup ISO GO:0005576 extracellular region IEA GO:0005615 extracellular space IDA GO:0005615 extracellular space ISO GO:0005615 extracellular space TAS GO:0005622 intracellular IEA GO:0005622 intracellular ISO GO:0005886 plasma membrane IEA GO:0005886 plasma membrane ISO GO:0005887 integral to plasma membrane IEA GO:0005887 integral to plasma membrane ISO GO:0009897 external side of plasma membrane IEA GO:0009897 external side of plasma membrane ISO GO:0009986 cell surface ISO GO:0016021 integral to membrane IDA GO:0045121 membrane raft IEA GO:0045121 membrane raft ISO GO:0055037 recycling endosome IEA GO:0055037 recycling endosome ISO molecular_function GO:0002020 protease binding IEA GO:0002020 protease binding ISO GO:0005125 cytokine activity ISO GO:0005125 cytokine activity TAS GO:0005164 tumor necrosis factor receptor binding IDA GO:0005164 tumor necrosis factor receptor binding IPI GO:0005164 tumor necrosis factor receptor binding ISO GO:0005164 tumor necrosis factor receptor binding TAS GO:0042802 identical protein binding IEA GO:0042802 identical protein binding ISO GO:0044212 transcription regulatory region DNA binding ISO

Protein-protein interaction details for Tnf (Rattus norvegicus) (Information is obtained from BioGRID)

Not available