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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Jak2 (Rattus norvegicus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000186activation of MAPKK activityIMP
GO:0006915apoptosisISO
GO:0006979response to oxidative stressIMP
GO:0007165signal transductionISO
GO:0007165signal transductionISS
GO:0007167enzyme linked receptor protein signaling pathwayISO
GO:0007186G-protein coupled receptor protein signaling pathwayIMP
GO:0007204elevation of cytosolic calcium ion concentrationIMP
GO:0007243intracellular protein kinase cascadeIEA
GO:0007243intracellular protein kinase cascadeISO
GO:0007259JAK-STAT cascadeIDA
GO:0007259JAK-STAT cascadeISO
GO:0007260tyrosine phosphorylation of STAT proteinISO
GO:0007262STAT protein import into nucleusISO
GO:0008284positive regulation of cell proliferationIMP
GO:0008285negative regulation of cell proliferationISO
GO:0008631induction of apoptosis by oxidative stressIMP
GO:0008636activation of caspase activity by protein phosphorylationISO
GO:0009755hormone-mediated signaling pathwayIDA
GO:0010811positive regulation of cell-substrate adhesionIEA
GO:0010811positive regulation of cell-substrate adhesionISO
GO:0014068positive regulation of phosphatidylinositol 3-kinase cascadeISO
GO:0016568chromatin modificationIEA
GO:0018108peptidyl-tyrosine phosphorylationISO
GO:0019221cytokine-mediated signaling pathwayISO
GO:0019221cytokine-mediated signaling pathwayISS
GO:0022408negative regulation of cell-cell adhesionIMP
GO:0030099myeloid cell differentiationISO
GO:0030154cell differentiationISO
GO:0030218erythrocyte differentiationISO
GO:0030218erythrocyte differentiationISS
GO:0030335positive regulation of cell migrationIMP
GO:0031103axon regenerationIMP
GO:0031959mineralocorticoid receptor signaling pathwayIMP
GO:0032024positive regulation of insulin secretionIMP
GO:0032496response to lipopolysaccharideISO
GO:0032516positive regulation of phosphoprotein phosphatase activityIMP
GO:0032731positive regulation of interleukin-1 beta productionIMP
GO:0032760positive regulation of tumor necrosis factor productionISO
GO:0033160positive regulation of protein import into nucleus, translocationIMP
GO:0033194response to hydroperoxideIMP
GO:0033209tumor necrosis factor-mediated signaling pathwayIEA
GO:0033209tumor necrosis factor-mediated signaling pathwayISO
GO:0034612response to tumor necrosis factorIEA
GO:0034612response to tumor necrosis factorISO
GO:0035409histone H3-Y41 phosphorylationISO
GO:0035409histone H3-Y41 phosphorylationISS
GO:0035722interleukin-12-mediated signaling pathwayIEA
GO:0035722interleukin-12-mediated signaling pathwayISO
GO:0042503tyrosine phosphorylation of Stat3 proteinIMP
GO:0042508tyrosine phosphorylation of Stat1 proteinIMP
GO:0042517positive regulation of tyrosine phosphorylation of Stat3 proteinISO
GO:0042517positive regulation of tyrosine phosphorylation of Stat3 proteinISS
GO:0042523positive regulation of tyrosine phosphorylation of Stat5 proteinISO
GO:0042977activation of JAK2 kinase activityISO
GO:0042977activation of JAK2 kinase activityISS
GO:0043065positive regulation of apoptosisIMP
GO:0043065positive regulation of apoptosisISO
GO:0043388positive regulation of DNA bindingIMP
GO:0043392negative regulation of DNA bindingISO
GO:0043526neuroprotectionIMP
GO:0045429positive regulation of nitric oxide biosynthetic processIMP
GO:0045597positive regulation of cell differentiationIMP
GO:0045822negative regulation of heart contractionIMP
GO:0046677response to antibioticIEA
GO:0046677response to antibioticISO
GO:0046777protein autophosphorylationIMP
GO:0046777protein autophosphorylationISO
GO:0046777protein autophosphorylationISS
GO:0048008platelet-derived growth factor receptor signaling pathwayIMP
GO:0050727regulation of inflammatory responseIEA
GO:0050727regulation of inflammatory responseISO
GO:0050729positive regulation of inflammatory responseIMP
GO:0050731positive regulation of peptidyl-tyrosine phosphorylationISO
GO:0050867positive regulation of cell activationIMP
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activityIMP
GO:0051770positive regulation of nitric-oxide synthase biosynthetic processIDA
GO:0051770positive regulation of nitric-oxide synthase biosynthetic processISO
GO:0060333interferon-gamma-mediated signaling pathwayIDA
GO:0060396growth hormone receptor signaling pathwayIEA
GO:0060396growth hormone receptor signaling pathwayISO
GO:0060397JAK-STAT cascade involved in growth hormone signaling pathwayISO
GO:0060397JAK-STAT cascade involved in growth hormone signaling pathwayISS
GO:0060399positive regulation of growth hormone receptor signaling pathwayISO
GO:0061180mammary gland epithelium developmentISO
GO:0070671response to interleukin-12IEA
GO:0070671response to interleukin-12ISO
cellular_component
GO:0005624membrane fractionIDA
GO:0005634nucleusIDA
GO:0005634nucleusISO
GO:0005634nucleusISS
GO:0005737cytoplasmIDA
GO:0005737cytoplasmISO
GO:0005829cytosolIDA
GO:0005856cytoskeletonIEA
GO:0005901caveolaISO
GO:0012505endomembrane systemIEA
GO:0016020membraneIEA
GO:0016363nuclear matrixIDA
GO:0045121membrane raftISO
molecular_function
GO:0000166nucleotide bindingIEA
GO:0004713protein tyrosine kinase activityIMP
GO:0004713protein tyrosine kinase activityISO
GO:0004713protein tyrosine kinase activityISS
GO:0004715non-membrane spanning protein tyrosine kinase activityIEA
GO:0005102receptor bindingISO
GO:0005131growth hormone receptor bindingIPI
GO:0005143interleukin-12 receptor bindingISO
GO:0005524ATP bindingIEA
GO:0008022protein C-terminus bindingIPI
GO:0019901protein kinase bindingIEA
GO:0019901protein kinase bindingISO
GO:0020037heme bindingIEA
GO:0020037heme bindingISO
GO:0020037heme bindingISS
GO:0031702type 1 angiotensin receptor bindingIPI
GO:0033130acetylcholine receptor bindingIPI
GO:0035401histone kinase activity (H3-Y41 specific)IEA
GO:0035401histone kinase activity (H3-Y41 specific)ISO
GO:0035401histone kinase activity (H3-Y41 specific)ISS
GO:0042169SH2 domain bindingIEA
GO:0042169SH2 domain bindingISO
GO:0042393histone bindingIEA
GO:0042393histone bindingISO
GO:0042393histone bindingISS
GO:0043548phosphatidylinositol 3-kinase bindingIPI
GO:0043560insulin receptor substrate bindingIPI
GO:0051428peptide hormone receptor bindingIPI

Protein-protein interaction details for Jak2 (Rattus norvegicus)
(Information is obtained from BioGRID)
Not available