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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for Shh (
Mus musculus
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000122
negative regulation of transcription from RNA polymerase II promoter
IDA
GO:0001525
angiogenesis
IDA
GO:0001525
angiogenesis
IGI
GO:0001525
angiogenesis
IMP
GO:0001569
patterning of blood vessels
IMP
GO:0001570
vasculogenesis
IDA
GO:0001656
metanephros development
IMP
GO:0001658
branching involved in ureteric bud morphogenesis
IMP
GO:0001708
cell fate specification
IGI
GO:0001708
cell fate specification
IMP
GO:0001755
neural crest cell migration
IMP
GO:0001822
kidney development
IMP
GO:0001841
neural tube formation
ISO
GO:0001942
hair follicle development
IMP
GO:0001944
vasculature development
IMP
GO:0001947
heart looping
IMP
GO:0002052
positive regulation of neuroblast proliferation
IDA
GO:0002052
positive regulation of neuroblast proliferation
ISO
GO:0002053
positive regulation of mesenchymal cell proliferation
IMP
GO:0002076
osteoblast development
IDA
GO:0002320
lymphoid progenitor cell differentiation
IMP
GO:0002320
lymphoid progenitor cell differentiation
ISO
GO:0003140
determination of left/right asymmetry in lateral mesoderm
IMP
GO:0006355
regulation of transcription, DNA-dependent
IMP
GO:0006508
proteolysis
IEA
GO:0006897
endocytosis
IDA
GO:0006915
apoptosis
IGI
GO:0007154
cell communication
IEA
GO:0007165
signal transduction
ISO
GO:0007165
signal transduction
TAS
GO:0007224
smoothened signaling pathway
IDA
GO:0007224
smoothened signaling pathway
IGI
GO:0007224
smoothened signaling pathway
IMP
GO:0007228
positive regulation of hh target transcription factor activity
IDA
GO:0007228
positive regulation of hh target transcription factor activity
IGI
GO:0007228
positive regulation of hh target transcription factor activity
IMP
GO:0007267
cell-cell signaling
IMP
GO:0007275
multicellular organismal development
IEA
GO:0007368
determination of left/right symmetry
IMP
GO:0007389
pattern specification process
IGI
GO:0007389
pattern specification process
IMP
GO:0007398
ectoderm development
IMP
GO:0007405
neuroblast proliferation
IDA
GO:0007411
axon guidance
IDA
GO:0007411
axon guidance
IMP
GO:0007417
central nervous system development
IMP
GO:0007442
hindgut morphogenesis
IMP
GO:0007502
digestive tract mesoderm development
ISO
GO:0007507
heart development
IMP
GO:0007596
blood coagulation
IMP
GO:0008209
androgen metabolic process
IMP
GO:0008219
cell death
IMP
GO:0008283
cell proliferation
IGI
GO:0008284
positive regulation of cell proliferation
IDA
GO:0008284
positive regulation of cell proliferation
IGI
GO:0008284
positive regulation of cell proliferation
IMP
GO:0008284
positive regulation of cell proliferation
ISO
GO:0009790
embryo development
IGI
GO:0009790
embryo development
IMP
GO:0009952
anterior/posterior pattern specification
IMP
GO:0009953
dorsal/ventral pattern formation
IGI
GO:0010463
mesenchymal cell proliferation
IMP
GO:0010468
regulation of gene expression
IGI
GO:0010468
regulation of gene expression
IMP
GO:0010468
regulation of gene expression
ISO
GO:0010628
positive regulation of gene expression
IMP
GO:0010629
negative regulation of gene expression
IMP
GO:0014003
oligodendrocyte development
IDA
GO:0014706
striated muscle tissue development
IMP
GO:0014858
positive regulation of skeletal muscle cell proliferation
IMP
GO:0014902
myotube differentiation
IMP
GO:0016539
intein-mediated protein splicing
IEA
GO:0021513
spinal cord dorsal/ventral patterning
IMP
GO:0021513
spinal cord dorsal/ventral patterning
ISO
GO:0021521
ventral spinal cord interneuron specification
ISO
GO:0021904
dorsal/ventral neural tube patterning
IDA
GO:0021904
dorsal/ventral neural tube patterning
IGI
GO:0021938
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
IDA
GO:0021938
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
IMP
GO:0021940
positive regulation of cerebellar granule cell precursor proliferation
IDA
GO:0021978
telencephalon regionalization
IMP
GO:0021978
telencephalon regionalization
ISO
GO:0030010
establishment of cell polarity
IDA
GO:0030162
regulation of proteolysis
IDA
GO:0030177
positive regulation of Wnt receptor signaling pathway
IMP
GO:0030178
negative regulation of Wnt receptor signaling pathway
IDA
GO:0030323
respiratory tube development
IMP
GO:0030324
lung development
IGI
GO:0030324
lung development
IMP
GO:0030326
embryonic limb morphogenesis
IGI
GO:0030326
embryonic limb morphogenesis
IMP
GO:0030336
negative regulation of cell migration
IDA
GO:0030539
male genitalia development
IMP
GO:0030850
prostate gland development
IMP
GO:0030878
thyroid gland development
IMP
GO:0030900
forebrain development
IGI
GO:0030901
midbrain development
IGI
GO:0030902
hindbrain development
IGI
GO:0030902
hindbrain development
IMP
GO:0031016
pancreas development
IGI
GO:0031016
pancreas development
IMP
GO:0031069
hair follicle morphogenesis
IMP
GO:0032435
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
IMP
GO:0033077
T cell differentiation in thymus
IMP
GO:0033089
positive regulation of T cell differentiation in thymus
IMP
GO:0033092
positive regulation of immature T cell proliferation in thymus
IMP
GO:0034244
negative regulation of transcription elongation from RNA polymerase II promoter
IDA
GO:0034504
protein localization to nucleus
IDA
GO:0035115
embryonic forelimb morphogenesis
IMP
GO:0035116
embryonic hindlimb morphogenesis
IMP
GO:0042127
regulation of cell proliferation
IDA
GO:0042127
regulation of cell proliferation
ISO
GO:0042130
negative regulation of T cell proliferation
IMP
GO:0042177
negative regulation of protein catabolic process
IMP
GO:0042307
positive regulation of protein import into nucleus
IGI
GO:0042475
odontogenesis of dentine-containing tooth
IMP
GO:0042476
odontogenesis
IDA
GO:0042733
embryonic digit morphogenesis
IGI
GO:0042981
regulation of apoptosis
IGI
GO:0043010
camera-type eye development
IDA
GO:0043010
camera-type eye development
IGI
GO:0043010
camera-type eye development
IMP
GO:0043066
negative regulation of apoptosis
ISO
GO:0043369
CD4-positive or CD8-positive, alpha-beta T cell lineage commitment
IMP
GO:0043369
CD4-positive or CD8-positive, alpha-beta T cell lineage commitment
ISO
GO:0043587
tongue morphogenesis
ISO
GO:0043588
skin development
IMP
GO:0045059
positive thymic T cell selection
IMP
GO:0045060
negative thymic T cell selection
IMP
GO:0045109
intermediate filament organization
IMP
GO:0045165
cell fate commitment
IGI
GO:0045445
myoblast differentiation
IDA
GO:0045471
response to ethanol
ISO
GO:0045596
negative regulation of cell differentiation
IDA
GO:0045596
negative regulation of cell differentiation
IMP
GO:0045597
positive regulation of cell differentiation
IMP
GO:0045666
positive regulation of neuron differentiation
ISO
GO:0045880
positive regulation of smoothened signaling pathway
IMP
GO:0045893
positive regulation of transcription, DNA-dependent
IDA
GO:0045893
positive regulation of transcription, DNA-dependent
ISO
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IDA
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IGI
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IMP
GO:0046534
positive regulation of photoreceptor cell differentiation
ISO
GO:0046638
positive regulation of alpha-beta T cell differentiation
IMP
GO:0046639
negative regulation of alpha-beta T cell differentiation
IMP
GO:0048468
cell development
IMP
GO:0048538
thymus development
IMP
GO:0048546
digestive tract morphogenesis
IMP
GO:0048557
embryonic digestive tract morphogenesis
IMP
GO:0048568
embryonic organ development
IMP
GO:0048589
developmental growth
IMP
GO:0048598
embryonic morphogenesis
IMP
GO:0048617
embryonic foregut morphogenesis
IMP
GO:0048643
positive regulation of skeletal muscle tissue development
IMP
GO:0048645
organ formation
IMP
GO:0048646
anatomical structure formation involved in morphogenesis
IMP
GO:0048663
neuron fate commitment
IMP
GO:0048678
response to axon injury
ISO
GO:0048706
embryonic skeletal system development
IGI
GO:0048709
oligodendrocyte differentiation
IGI
GO:0048714
positive regulation of oligodendrocyte differentiation
IDA
GO:0048754
branching morphogenesis of a tube
IMP
GO:0048808
male genitalia morphogenesis
ISO
GO:0048839
inner ear development
IGI
GO:0048839
inner ear development
IMP
GO:0048856
anatomical structure development
IMP
GO:0048859
formation of anatomical boundary
IMP
GO:0048864
stem cell development
IMP
GO:0051146
striated muscle cell differentiation
IDA
GO:0051146
striated muscle cell differentiation
IMP
GO:0051155
positive regulation of striated muscle cell differentiation
IMP
GO:0060020
Bergmann glial cell differentiation
IDA
GO:0060021
palate development
IMP
GO:0060070
canonical Wnt receptor signaling pathway
IDA
GO:0060173
limb development
IGI
GO:0060173
limb development
IMP
GO:0060174
limb bud formation
IMP
GO:0060406
positive regulation of penile erection
ISO
GO:0060425
lung morphogenesis
IMP
GO:0060428
lung epithelium development
IMP
GO:0060438
trachea development
IMP
GO:0060439
trachea morphogenesis
IMP
GO:0060441
epithelial tube branching involved in lung morphogenesis
IMP
GO:0060442
branching involved in prostate gland morphogenesis
IDA
GO:0060445
branching involved in salivary gland morphogenesis
IGI
GO:0060445
branching involved in salivary gland morphogenesis
IMP
GO:0060447
bud outgrowth involved in lung branching
IMP
GO:0060458
right lung development
IMP
GO:0060459
left lung development
IMP
GO:0060463
lung lobe morphogenesis
IMP
GO:0060484
lung-associated mesenchyme development
IMP
GO:0060513
prostatic bud formation
IGI
GO:0060516
primary prostatic bud elongation
IDA
GO:0060523
prostate epithelial cord elongation
IDA
GO:0060662
salivary gland cavitation
IDA
GO:0060664
epithelial cell proliferation involved in salivary gland morphogenesis
IMP
GO:0060684
epithelial-mesenchymal cell signaling
IMP
GO:0060685
regulation of prostatic bud formation
IDA
GO:0060685
regulation of prostatic bud formation
IMP
GO:0060738
epithelial-mesenchymal signaling involved in prostate gland development
IGI
GO:0060738
epithelial-mesenchymal signaling involved in prostate gland development
ISO
GO:0060768
regulation of epithelial cell proliferation involved in prostate gland development
IMP
GO:0060769
positive regulation of epithelial cell proliferation involved in prostate gland development
IMP
GO:0060782
regulation of mesenchymal cell proliferation involved in prostate gland development
IMP
GO:0060783
mesenchymal smoothened signaling pathway involved in prostate gland development
IMP
GO:0060840
artery development
IGI
GO:0060840
artery development
IMP
GO:0060916
mesenchymal cell proliferation involved in lung development
IDA
GO:0061053
somite development
IMP
GO:0061056
sclerotome development
ISO
GO:0070447
positive regulation of oligodendrocyte progenitor proliferation
ISO
GO:0071285
cellular response to lithium ion
IDA
GO:0072136
metanephric mesenchymal cell proliferation involved in metanephros development
IMP
GO:0080125
multicellular structure septum development
IMP
GO:0090090
negative regulation of canonical Wnt receptor signaling pathway
IMP
GO:2000062
negative regulation of ureter smooth muscle cell differentiation
IDA
GO:2000063
positive regulation of ureter smooth muscle cell differentiation
IMP
GO:2000357
negative regulation of kidney smooth muscle cell differentiation
IDA
GO:2000358
positive regulation of kidney smooth muscle cell differentiation
IDA
GO:2000729
positive regulation of mesenchymal cell proliferation involved in ureter development
IMP
cellular_component
GO:0005576
extracellular region
IEA
GO:0005615
extracellular space
IDA
GO:0005615
extracellular space
ISO
GO:0005624
membrane fraction
IDA
GO:0005634
nucleus
IDA
GO:0005783
endoplasmic reticulum
ISO
GO:0005794
Golgi apparatus
ISO
GO:0005886
plasma membrane
IEA
GO:0009986
cell surface
IDA
GO:0016020
membrane
IEA
GO:0030133
transport vesicle
ISO
GO:0031012
extracellular matrix
IDA
GO:0045121
membrane raft
IDA
GO:0045121
membrane raft
ISO
molecular_function
GO:0001948
glycoprotein binding
IDA
GO:0004871
signal transducer activity
ISO
GO:0005113
patched binding
IPI
GO:0005113
patched binding
ISO
GO:0005509
calcium ion binding
ISO
GO:0005515
protein binding
IPI
GO:0005539
glycosaminoglycan binding
IDA
GO:0008233
peptidase activity
IEA
GO:0008270
zinc ion binding
ISO
GO:0016787
hydrolase activity
IDA
GO:0043237
laminin-1 binding
IDA
Protein-protein interaction details for Shh (
Mus musculus
)
(Information is obtained from BioGRID)
Not available