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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for EGFR (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000902 cell morphogenesis IEA GO:0001503 ossification NAS GO:0001892 embryonic placenta development IEA GO:0001942 hair follicle development IEA GO:0006468 protein phosphorylation IEA GO:0006950 response to stress NAS GO:0007165 signal transduction IDA GO:0007165 signal transduction TAS GO:0007166 cell surface receptor linked signaling pathway IDA GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA GO:0007173 epidermal growth factor receptor signaling pathway IDA GO:0007173 epidermal growth factor receptor signaling pathway NAS GO:0007173 epidermal growth factor receptor signaling pathway TAS GO:0007202 activation of phospholipase C activity TAS GO:0007411 axon guidance TAS GO:0007435 salivary gland morphogenesis IEA GO:0008283 cell proliferation TAS GO:0008284 positive regulation of cell proliferation IDA GO:0016337 cell-cell adhesion IMP GO:0021795 cerebral cortex cell migration IEA GO:0030335 positive regulation of cell migration IMP GO:0031659 positive regulation of cyclin-dependent protein kinase activity involved in G1/S IDA GO:0035413 positive regulation of catenin import into nucleus IMP GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway TAS GO:0042327 positive regulation of phosphorylation IDA GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling TAS GO:0043066 negative regulation of apoptosis IMP GO:0043406 positive regulation of MAP kinase activity IDA GO:0045429 positive regulation of nitric oxide biosynthetic process IDA GO:0046777 protein autophosphorylation IEA GO:0046777 protein autophosphorylation IMP GO:0048146 positive regulation of fibroblast proliferation IEA GO:0048546 digestive tract morphogenesis IEA GO:0050679 positive regulation of epithelial cell proliferation IDA GO:0050679 positive regulation of epithelial cell proliferation IEA GO:0050730 regulation of peptidyl-tyrosine phosphorylation IEA GO:0050730 regulation of peptidyl-tyrosine phosphorylation IMP GO:0050999 regulation of nitric-oxide synthase activity IDA GO:0051205 protein insertion into membrane TAS GO:0051897 positive regulation of protein kinase B signaling cascade IMP GO:0060571 morphogenesis of an epithelial fold IEA GO:0070141 response to UV-A IDA cellular_component GO:0000139 Golgi membrane IEA GO:0005576 extracellular region IEA GO:0005615 extracellular space NAS GO:0005622 intracellular IEA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005737 cytoplasm IDA GO:0005768 endosome IDA GO:0005783 endoplasmic reticulum IEA GO:0005789 endoplasmic reticulum membrane IEA GO:0005794 Golgi apparatus IEA GO:0005886 plasma membrane IDA GO:0005886 plasma membrane IEA GO:0005886 plasma membrane TAS GO:0016020 membrane IDA GO:0016020 membrane IEA GO:0016021 integral to membrane IEA GO:0016323 basolateral plasma membrane IDA GO:0016323 basolateral plasma membrane IEA GO:0030122 AP-2 adaptor complex TAS GO:0030139 endocytic vesicle IEA GO:0031965 nuclear membrane IEA GO:0045121 membrane raft IDA GO:0048471 perinuclear region of cytoplasm IEA GO:0070435 Shc-EGFR complex ISS molecular_function GO:0000166 nucleotide binding IEA GO:0003690 double-stranded DNA binding NAS GO:0004710 MAP/ERK kinase kinase activity NAS GO:0004713 protein tyrosine kinase activity IDA GO:0004713 protein tyrosine kinase activity IMP GO:0004713 protein tyrosine kinase activity TAS GO:0004714 transmembrane receptor protein tyrosine kinase activity IEA GO:0004714 transmembrane receptor protein tyrosine kinase activity TAS GO:0004716 receptor signaling protein tyrosine kinase activity IEA GO:0004871 signal transducer activity IEA GO:0004872 receptor activity IEA GO:0004888 transmembrane signaling receptor activity IDA GO:0005006 epidermal growth factor-activated receptor activity IDA GO:0005006 epidermal growth factor-activated receptor activity IEA GO:0005006 epidermal growth factor-activated receptor activity NAS GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0016301 kinase activity IEA GO:0019899 enzyme binding IPI GO:0019903 protein phosphatase binding IPI GO:0030235 nitric-oxide synthase regulator activity IDA GO:0042802 identical protein binding IPI GO:0046982 protein heterodimerization activity IDA GO:0051015 actin filament binding IDA

Protein-protein interaction details for EGFR (Homo sapiens) (Information is obtained from BioGRID)

Not available