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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Jak3 (Mus musculus) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0002731 negative regulation of dendritic cell cytokine production IMP GO:0006468 protein phosphorylation IEA GO:0007167 enzyme linked receptor protein signaling pathway IDA GO:0007204 elevation of cytosolic calcium ion concentration ISO GO:0007243 intracellular protein kinase cascade IDA GO:0016310 phosphorylation IEA GO:0018108 peptidyl-tyrosine phosphorylation IDA GO:0019221 cytokine-mediated signaling pathway IDA GO:0019221 cytokine-mediated signaling pathway ISO GO:0030183 B cell differentiation IMP GO:0032693 negative regulation of interleukin-10 production IMP GO:0032695 negative regulation of interleukin-12 production IMP GO:0042102 positive regulation of T cell proliferation ISO GO:0042104 positive regulation of activated T cell proliferation ISO GO:0042506 tyrosine phosphorylation of Stat5 protein ISO GO:0042981 regulation of apoptosis IMP GO:0043029 T cell homeostasis IMP GO:0045221 negative regulation of FasL biosynthetic process IMP GO:0045626 negative regulation of T-helper 1 cell differentiation IMP GO:0045768 positive regulation of anti-apoptosis IMP GO:0045944 positive regulation of transcription from RNA polymerase II promoter IMP GO:0046777 protein autophosphorylation ISO GO:0048535 lymph node development TAS GO:0050778 positive regulation of immune response ISO GO:0050868 negative regulation of T cell activation IMP GO:0051928 positive regulation of calcium ion transport ISO GO:0070232 regulation of T cell apoptosis IMP GO:0070244 negative regulation of thymocyte apoptosis IMP GO:0070669 response to interleukin-2 TAS GO:0070670 response to interleukin-4 ISO GO:0070670 response to interleukin-4 TAS GO:0070672 response to interleukin-15 TAS GO:0071104 response to interleukin-9 TAS cellular_component GO:0005622 intracellular IC GO:0005737 cytoplasm ISO GO:0005856 cytoskeleton IEA GO:0016020 membrane IEA molecular_function GO:0000166 nucleotide binding IEA GO:0004672 protein kinase activity IEA GO:0004713 protein tyrosine kinase activity IDA GO:0004713 protein tyrosine kinase activity ISO GO:0004715 non-membrane spanning protein tyrosine kinase activity IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0016301 kinase activity IEA GO:0016740 transferase activity IEA GO:0016772 transferase activity, transferring phosphorus-containing groups IEA

Protein-protein interaction details for Jak3 (Mus musculus) (Information is obtained from BioGRID)

Not available