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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Itch (Mus musculus) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000209 protein polyubiquitination IDA GO:0002669 positive regulation of T cell anergy IMP GO:0006464 protein modification process IEA GO:0006511 ubiquitin-dependent protein catabolic process IDA GO:0006511 ubiquitin-dependent protein catabolic process ISA GO:0006915 apoptosis IEA GO:0009615 response to virus IEA GO:0016567 protein ubiquitination ISA GO:0016567 protein ubiquitination ISO GO:0016567 protein ubiquitination ISS GO:0032088 negative regulation of NF-kappaB transcription factor activity IMP GO:0035519 protein K29-linked ubiquitination ISO GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process IDA GO:0043066 negative regulation of apoptosis ISO GO:0045087 innate immune response IEA GO:0045732 positive regulation of protein catabolic process IDA GO:0045732 positive regulation of protein catabolic process IMP GO:0046329 negative regulation of JNK cascade IMP GO:0046642 negative regulation of alpha-beta T cell proliferation IMP GO:0050687 negative regulation of defense response to virus IMP GO:0050687 negative regulation of defense response to virus ISO GO:0070534 protein K63-linked ubiquitination ISO GO:0070936 protein K48-linked ubiquitination IMP GO:0070936 protein K48-linked ubiquitination ISO GO:0090085 regulation of protein deubiquitination IMP cellular_component GO:0000151 ubiquitin ligase complex ISA GO:0005622 intracellular IEA GO:0005624 membrane fraction IDA GO:0005634 nucleus IDA GO:0005737 cytoplasm IDA GO:0005737 cytoplasm ISO GO:0005886 plasma membrane ISO GO:0005938 cell cortex IDA GO:0016020 membrane IEA GO:0031410 cytoplasmic vesicle IDA molecular_function GO:0004842 ubiquitin-protein ligase activity IBA GO:0004842 ubiquitin-protein ligase activity ISA GO:0004842 ubiquitin-protein ligase activity ISO GO:0005515 protein binding IPI GO:0016874 ligase activity IMP GO:0016881 acid-amino acid ligase activity IEA GO:0043021 ribonucleoprotein binding ISO GO:0045236 CXCR chemokine receptor binding ISO

Protein-protein interaction details for Itch (Mus musculus) (Information is obtained from BioGRID)

Not available