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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Il6 (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001781neutrophil apoptosisIDA
GO:0001781neutrophil apoptosisIMP
GO:0001781neutrophil apoptosisISO
GO:0002384hepatic immune responseISO
GO:0002675positive regulation of acute inflammatory responseISO
GO:0006469negative regulation of protein kinase activityISO
GO:0006953acute-phase responseIEA
GO:0006954inflammatory responseISO
GO:0006955immune responseIEA
GO:0008284positive regulation of cell proliferationISO
GO:0008285negative regulation of cell proliferationISO
GO:0008360regulation of cell shapeISO
GO:0009611response to woundingIDA
GO:0010574regulation of vascular endothelial growth factor productionISO
GO:0010628positive regulation of gene expressionISO
GO:0016049cell growthISO
GO:0019221cytokine-mediated signaling pathwayISO
GO:0031018endocrine pancreas developmentIMP
GO:0031175neuron projection developmentISO
GO:0032722positive regulation of chemokine productionISO
GO:0032755positive regulation of interleukin-6 productionISO
GO:0032966negative regulation of collagen biosynthetic processISO
GO:0033138positive regulation of peptidyl-serine phosphorylationISO
GO:0033160positive regulation of protein import into nucleus, translocationISO
GO:0042102positive regulation of T cell proliferationISO
GO:0042127regulation of cell proliferationIGI
GO:0042517positive regulation of tyrosine phosphorylation of Stat3 proteinISO
GO:0042832defense response to protozoanIMP
GO:0042981regulation of apoptosisIMP
GO:0042981regulation of apoptosisISO
GO:0043066negative regulation of apoptosisISO
GO:0043154negative regulation of caspase activityISO
GO:0043410positive regulation of MAPKKK cascadeISO
GO:0043526neuroprotectionISO
GO:0045079negative regulation of chemokine biosynthetic processIDA
GO:0045079negative regulation of chemokine biosynthetic processIMP
GO:0045188regulation of circadian sleep/wake cycle, non-REM sleepISO
GO:0045429positive regulation of nitric oxide biosynthetic processISO
GO:0045454cell redox homeostasisISO
GO:0045630positive regulation of T-helper 2 cell differentiationIDA
GO:0045666positive regulation of neuron differentiationISO
GO:0045721negative regulation of gluconeogenesisISO
GO:0045727positive regulation of translationISO
GO:0045740positive regulation of DNA replicationISO
GO:0045768positive regulation of anti-apoptosisISO
GO:0045893positive regulation of transcription, DNA-dependentIDA
GO:0045893positive regulation of transcription, DNA-dependentISO
GO:0045944positive regulation of transcription from RNA polymerase II promoterIGI
GO:0045944positive regulation of transcription from RNA polymerase II promoterISO
GO:0046427positive regulation of JAK-STAT cascadeISO
GO:0046716muscle cell homeostasisIGI
GO:0046888negative regulation of hormone secretionIDA
GO:0048635negative regulation of muscle organ developmentISO
GO:0048661positive regulation of smooth muscle cell proliferationISO
GO:0050679positive regulation of epithelial cell proliferationIDA
GO:0050679positive regulation of epithelial cell proliferationIMP
GO:0050710negative regulation of cytokine secretionISO
GO:0050731positive regulation of peptidyl-tyrosine phosphorylationISO
GO:0050871positive regulation of B cell activationISO
GO:0051024positive regulation of immunoglobulin secretionISO
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activityISO
GO:0051384response to glucocorticoid stimulusISO
GO:0051607defense response to virusISO
GO:0051897positive regulation of protein kinase B signaling cascadeISO
GO:0051971positive regulation of transmission of nerve impulseISO
GO:0060445branching involved in salivary gland morphogenesisIDA
GO:0060445branching involved in salivary gland morphogenesisIMP
GO:0060664epithelial cell proliferation involved in salivary gland morphogenesisIDA
GO:0070091glucagon secretionIMP
GO:0070102interleukin-6-mediated signaling pathwayIDA
GO:0070102interleukin-6-mediated signaling pathwayISO
GO:0070301cellular response to hydrogen peroxideISO
GO:0070374positive regulation of ERK1 and ERK2 cascadeISO
cellular_component
GO:0005576extracellular regionIEA
GO:0005615extracellular spaceIDA
GO:0005615extracellular spaceISO
GO:0005896interleukin-6 receptor complexISO
GO:0009897external side of plasma membraneIDA
molecular_function
GO:0005102receptor bindingISO
GO:0005125cytokine activityIDA
GO:0005125cytokine activityISO
GO:0005138interleukin-6 receptor bindingIDA
GO:0005138interleukin-6 receptor bindingISO
GO:0005515protein bindingIPI
GO:0008083growth factor activityISO

Protein-protein interaction details for Il6 (Mus musculus)
(Information is obtained from BioGRID)
Not available