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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Irak1 (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001959regulation of cytokine-mediated signaling pathwayISO
GO:0006468protein phosphorylationIEA
GO:0006468protein phosphorylationISO
GO:0007165signal transductionIEA
GO:0007250activation of NF-kappaB-inducing kinase activityISO
GO:0007254JNK cascadeISO
GO:0016310phosphorylationIEA
GO:0019221cytokine-mediated signaling pathwayIDA
GO:0019221cytokine-mediated signaling pathwayISO
GO:0031663lipopolysaccharide-mediated signaling pathwayIDA
GO:0031663lipopolysaccharide-mediated signaling pathwayISO
GO:0032088negative regulation of NF-kappaB transcription factor activityISO
GO:0032494response to peptidoglycanIDA
GO:0032496response to lipopolysaccharideIDA
GO:0032496response to lipopolysaccharideISO
GO:0034134toll-like receptor 2 signaling pathwayIDA
GO:0034134toll-like receptor 2 signaling pathwayISO
GO:0034142toll-like receptor 4 signaling pathwayIDA
GO:0043406positive regulation of MAP kinase activityIMP
GO:0043507positive regulation of JUN kinase activityIMP
GO:0045892negative regulation of transcription, DNA-dependentIMP
GO:0045944positive regulation of transcription from RNA polymerase II promoterISO
GO:0046777protein autophosphorylationIDA
GO:0046777protein autophosphorylationISO
GO:0048661positive regulation of smooth muscle cell proliferationISO
GO:0051092positive regulation of NF-kappaB transcription factor activityIDA
GO:0051092positive regulation of NF-kappaB transcription factor activityISO
GO:0051259protein oligomerizationISO
GO:0070498interleukin-1-mediated signaling pathwayIDA
GO:0070498interleukin-1-mediated signaling pathwayISO
GO:0070555response to interleukin-1ISO
GO:0090370negative regulation of cholesterol effluxIMP
cellular_component
GO:0005624membrane fractionIDA
GO:0005625soluble fractionISO
molecular_function
GO:0000166nucleotide bindingIEA
GO:0004672protein kinase activityIDA
GO:0004672protein kinase activityISO
GO:0004674protein serine/threonine kinase activityIEA
GO:0004872receptor activityIEA
GO:0005149interleukin-1 receptor bindingIPI
GO:0005515protein bindingIPI
GO:0005524ATP bindingIEA
GO:0016301kinase activityISO
GO:0016740transferase activityIEA
GO:0016772transferase activity, transferring phosphorus-containing groupsIEA
GO:0042803protein homodimerization activityISO
GO:0046982protein heterodimerization activityISO

Protein-protein interaction details for Irak1 (Mus musculus)
(Information is obtained from BioGRID)
Not available