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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CYLD (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0002218activation of innate immune responseTAS
GO:0006412translationIEA
GO:0006511ubiquitin-dependent protein catabolic processIEA
GO:0006917induction of apoptosisIDA
GO:0007049cell cycleIEA
GO:0007346regulation of mitotic cell cycleIMP
GO:0016055Wnt receptor signaling pathwayIEA
GO:0032088negative regulation of NF-kappaB transcription factor activityIDA
GO:0032480negative regulation of type I interferon productionTAS
GO:0042347negative regulation of NF-kappaB import into nucleusIDA
GO:0045087innate immune responseTAS
GO:0070423nucleotide-binding oligomerization domain containing signaling pathwayTAS
GO:0070507regulation of microtubule cytoskeleton organizationIMP
GO:0070536protein K63-linked deubiquitinationIDA
GO:0090090negative regulation of canonical Wnt receptor signaling pathwayIMP
cellular_component
GO:0005622intracellularIEA
GO:0005737cytoplasmIEA
GO:0005829cytosolIDA
GO:0005829cytosolTAS
GO:0005840ribosomeIEA
GO:0005856cytoskeletonIEA
GO:0005881cytoplasmic microtubuleIDA
GO:0005886plasma membraneIEA
GO:0030496midbodyIDA
GO:0031234extrinsic to internal side of plasma membraneIDA
GO:0048471perinuclear region of cytoplasmIEA
molecular_function
GO:0003735structural constituent of ribosomeIEA
GO:0004221ubiquitin thiolesterase activityIEA
GO:0004843ubiquitin-specific protease activityIDA
GO:0005515protein bindingIPI
GO:0008233peptidase activityIEA
GO:0008234cysteine-type peptidase activityIEA
GO:0008270zinc ion bindingIDA
GO:0019901protein kinase bindingIPI
GO:0046872metal ion bindingIEA
GO:0070064proline-rich region bindingIPI

Protein-protein interaction details for CYLD (Homo sapiens)
(Information is obtained from BioGRID)
Not available