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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for NKX2-5 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IMP GO:0000122 negative regulation of transcription from RNA polymerase II promoter ISS GO:0001570 vasculogenesis ISS GO:0001947 heart looping ISS GO:0003007 heart morphogenesis ISS GO:0003148 outflow tract septum morphogenesis IMP GO:0003161 cardiac conduction system development IMP GO:0003162 atrioventricular node development IEA GO:0003166 bundle of His development IEA GO:0003168 cardiac Purkinje fiber cell differentiation IEA GO:0003211 cardiac ventricle formation IEA GO:0003221 right ventricular cardiac muscle tissue morphogenesis IMP GO:0003222 ventricular trabecular myocardium morphogenesis IEA GO:0003278 apoptosis involved in heart morphogenesis IEA GO:0003285 septum secundum development IMP GO:0003342 proepicardium development IEA GO:0003350 pulmonary myocardium development IEA GO:0006351 transcription, DNA-dependent IDA GO:0007275 multicellular organismal development IEA GO:0007512 adult heart development IMP GO:0008284 positive regulation of cell proliferation ISS GO:0010667 negative regulation of cardiac muscle cell apoptosis IMP GO:0010735 positive regulation of transcription via serum response element binding ISS GO:0010765 positive regulation of sodium ion transport ISS GO:0010832 negative regulation of myotube differentiation IMP GO:0030097 hemopoiesis ISS GO:0030154 cell differentiation ISS GO:0030509 BMP signaling pathway IEA GO:0030878 thyroid gland development IMP GO:0032355 response to estradiol stimulus IEA GO:0035050 embryonic heart tube development ISS GO:0043066 negative regulation of apoptosis ISS GO:0045666 positive regulation of neuron differentiation IMP GO:0045823 positive regulation of heart contraction ISS GO:0045885 positive regulation of survival gene product expression IMP GO:0045892 negative regulation of transcription, DNA-dependent ISS GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045893 positive regulation of transcription, DNA-dependent IMP GO:0045893 positive regulation of transcription, DNA-dependent ISS GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IGI GO:0045944 positive regulation of transcription from RNA polymerase II promoter IMP GO:0045944 positive regulation of transcription from RNA polymerase II promoter ISS GO:0048536 spleen development ISS GO:0051891 positive regulation of cardioblast differentiation ISS GO:0051929 positive regulation of calcium ion transport via voltage-gated calcium channel activity ISS GO:0055005 ventricular cardiac myofibril development IEA GO:0055007 cardiac muscle cell differentiation ISS GO:0055008 cardiac muscle tissue morphogenesis IMP GO:0055014 atrial cardiac muscle cell development ISS GO:0055015 ventricular cardiac muscle cell development ISS GO:0055117 regulation of cardiac muscle contraction ISS GO:0060037 pharyngeal system development ISS GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter ISS GO:0060347 heart trabecula formation IEA GO:0060412 ventricular septum morphogenesis IMP GO:0060413 atrial septum morphogenesis IMP GO:0060928 atrioventricular node cell development IEA GO:0060929 atrioventricular node cell fate commitment IEA GO:0060971 embryonic heart tube left/right pattern formation IEA GO:0090090 negative regulation of canonical Wnt receptor signaling pathway ISS cellular_component GO:0005634 nucleus IDA GO:0005667 transcription factor complex IC GO:0005737 cytoplasm IEA molecular_function GO:0003677 DNA binding IDA GO:0003677 DNA binding IEA GO:0003682 chromatin binding IDA GO:0003700 sequence-specific DNA binding transcription factor activity IDA GO:0003700 sequence-specific DNA binding transcription factor activity IMP GO:0005515 protein binding IPI GO:0008134 transcription factor binding IPI GO:0010736 serum response element binding ISS GO:0042803 protein homodimerization activity IEA GO:0043565 sequence-specific DNA binding IDA GO:0044212 transcription regulatory region DNA binding IDA GO:0046982 protein heterodimerization activity ISS

Protein-protein interaction details for NKX2-5 (Homo sapiens) (Information is obtained from BioGRID)

Not available