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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for Cdkn1a (
Mus musculus
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000079
regulation of cyclin-dependent protein kinase activity
IMP
GO:0000082
G1/S transition of mitotic cell cycle
ISO
GO:0000086
G2/M transition of mitotic cell cycle
ISO
GO:0001934
positive regulation of protein phosphorylation
ISO
GO:0006974
response to DNA damage stimulus
IMP
GO:0006974
response to DNA damage stimulus
ISO
GO:0006977
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
ISO
GO:0007049
cell cycle
IEA
GO:0007050
cell cycle arrest
IDA
GO:0007050
cell cycle arrest
ISO
GO:0007346
regulation of mitotic cell cycle
IMP
GO:0008285
negative regulation of cell proliferation
IMP
GO:0008285
negative regulation of cell proliferation
ISO
GO:0009411
response to UV
IMP
GO:0010629
negative regulation of gene expression
IMP
GO:0016310
phosphorylation
IEA
GO:0030308
negative regulation of cell growth
ISO
GO:0030890
positive regulation of B cell proliferation
IGI
GO:0031668
cellular response to extracellular stimulus
ISO
GO:0033158
regulation of protein import into nucleus, translocation
IMP
GO:0042326
negative regulation of phosphorylation
IDA
GO:0042326
negative regulation of phosphorylation
ISO
GO:0043066
negative regulation of apoptosis
IMP
GO:0043068
positive regulation of programmed cell death
IMP
GO:0043085
positive regulation of catalytic activity
ISO
GO:0043086
negative regulation of catalytic activity
IEA
GO:0045736
negative regulation of cyclin-dependent protein kinase activity
IDA
GO:0045768
positive regulation of anti-apoptosis
ISO
GO:0048146
positive regulation of fibroblast proliferation
ISO
GO:0051726
regulation of cell cycle
IDA
GO:0071479
cellular response to ionizing radiation
ISO
GO:0090398
cellular senescence
ISO
GO:2000278
regulation of DNA biosynthetic process
IMP
GO:2000379
positive regulation of reactive oxygen species metabolic process
ISO
cellular_component
GO:0000307
cyclin-dependent protein kinase holoenzyme complex
IPI
GO:0000307
cyclin-dependent protein kinase holoenzyme complex
ISO
GO:0005634
nucleus
IDA
GO:0005634
nucleus
ISO
GO:0005737
cytoplasm
IDA
GO:0005737
cytoplasm
ISO
GO:0005829
cytosol
IDA
GO:0070557
PCNA-p21 complex
ISO
molecular_function
GO:0004860
protein kinase inhibitor activity
IEA
GO:0004861
cyclin-dependent protein kinase inhibitor activity
IDA
GO:0005515
protein binding
IPI
GO:0016301
kinase activity
IEA
GO:0019912
cyclin-dependent protein kinase activating kinase activity
ISO
GO:0030332
cyclin binding
IPI
GO:0032403
protein complex binding
ISO
GO:0046872
metal ion binding
IEA
Protein-protein interaction details for Cdkn1a (
Mus musculus
)
(Information is obtained from BioGRID)
Not available