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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Brca1 (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000724double-strand break repair via homologous recombinationISO
GO:0006260DNA replicationIMP
GO:0006281DNA repairIEA
GO:0006301postreplication repairISO
GO:0006302double-strand break repairISO
GO:0006310DNA recombinationIEA
GO:0006349regulation of gene expression by genetic imprintingIMP
GO:0006633fatty acid biosynthetic processIEA
GO:0006974response to DNA damage stimulusIEA
GO:0007049cell cycleIEA
GO:0007059chromosome segregationISO
GO:0007098centrosome cycleIGI
GO:0008610lipid biosynthetic processIEA
GO:0008630DNA damage response, signal transduction resulting in induction of apoptosisISO
GO:0009048dosage compensation, by inactivation of X chromosomeIDA
GO:0010212response to ionizing radiationISO
GO:0016567protein ubiquitinationISO
GO:0031398positive regulation of protein ubiquitinationISO
GO:0031572G2/M transition DNA damage checkpointISO
GO:0034446substrate adhesion-dependent cell spreadingISO
GO:0035066positive regulation of histone acetylationIMP
GO:0035066positive regulation of histone acetylationISO
GO:0035067negative regulation of histone acetylationIMP
GO:0043009chordate embryonic developmentIMP
GO:0043627response to estrogen stimulusISO
GO:0044030regulation of DNA methylationIMP
GO:0045717negative regulation of fatty acid biosynthetic processISO
GO:0045739positive regulation of DNA repairISO
GO:0045892negative regulation of transcription, DNA-dependentISO
GO:0045944positive regulation of transcription from RNA polymerase II promoterIMP
GO:0045944positive regulation of transcription from RNA polymerase II promoterISO
GO:0051298centrosome duplicationTAS
GO:0051571positive regulation of histone H3-K4 methylationIMP
GO:0051571positive regulation of histone H3-K4 methylationISO
GO:0051572negative regulation of histone H3-K4 methylationIMP
GO:0051573negative regulation of histone H3-K9 methylationIMP
GO:0051573negative regulation of histone H3-K9 methylationISO
GO:0051574positive regulation of histone H3-K9 methylationIMP
GO:0051865protein autoubiquitinationISO
GO:0070512positive regulation of histone H4-K20 methylationIMP
GO:0070512positive regulation of histone H4-K20 methylationISO
GO:0071158positive regulation of cell cycle arrestISO
GO:0071681cellular response to indole-3-methanolISO
GO:0085020protein K6-linked ubiquitinationISO
GO:2000145regulation of cell motilityISO
GO:2000617positive regulation of histone H3-K9 acetylationIMP
GO:2000617positive regulation of histone H3-K9 acetylationISO
GO:2000620positive regulation of histone H4-K16 acetylationIMP
GO:2000620positive regulation of histone H4-K16 acetylationISO
cellular_component
GO:0000793condensed chromosomeIDA
GO:0000794condensed nuclear chromosomeIDA
GO:0001726ruffleISO
GO:0005622intracellularIEA
GO:0005634nucleusISO
GO:0005737cytoplasmIDA
GO:0005759mitochondrial matrixISO
GO:0005813centrosomeTAS
GO:0005886plasma membraneISO
GO:0030529ribonucleoprotein complexISO
GO:0031436BRCA1-BARD1 complexISO
GO:0043234protein complexISO
GO:0070531BRCA1-A complexISO
molecular_function
GO:0003677DNA bindingIEA
GO:0003684damaged DNA bindingIDA
GO:0003723RNA bindingISO
GO:0004842ubiquitin-protein ligase activityISO
GO:0008270zinc ion bindingIEA
GO:0016874ligase activityIEA
GO:0019899enzyme bindingISO
GO:0031625ubiquitin protein ligase bindingISO
GO:0044212transcription regulatory region DNA bindingIDA
GO:0044212transcription regulatory region DNA bindingISO
GO:0046872metal ion bindingIEA

Protein-protein interaction details for Brca1 (Mus musculus)
(Information is obtained from BioGRID)
Not available