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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TIRAP (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0002224toll-like receptor signaling pathwayTAS
GO:0002755MyD88-dependent toll-like receptor signaling pathwayTAS
GO:0006954inflammatory responseIEA
GO:0007165signal transductionIEA
GO:0007166cell surface receptor linked signaling pathwayISS
GO:0008063Toll signaling pathwayTAS
GO:0030099myeloid cell differentiationISS
GO:0030890positive regulation of B cell proliferationISS
GO:0032496response to lipopolysaccharideIDA
GO:0032648regulation of interferon-beta productionISS
GO:0032735positive regulation of interleukin-12 productionISS
GO:0032738positive regulation of interleukin-15 productionIDA
GO:0032757positive regulation of interleukin-8 productionIMP
GO:0032760positive regulation of tumor necrosis factor productionIMP
GO:0034130toll-like receptor 1 signaling pathwayTAS
GO:0034134toll-like receptor 2 signaling pathwayTAS
GO:0034137positive regulation of toll-like receptor 2 signaling pathwayIMP
GO:0034141positive regulation of toll-like receptor 3 signaling pathwayISS
GO:0034142toll-like receptor 4 signaling pathwayTAS
GO:0034145positive regulation of toll-like receptor 4 signaling pathwayIMP
GO:0035665TIRAP-dependent toll-like receptor 4 signaling pathwayIDA
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cascadeIMP
GO:0044130negative regulation of growth of symbiont in hostISS
GO:0045087innate immune responseIEA
GO:0045087innate immune responseTAS
GO:0045088regulation of innate immune responseIC
GO:0045410positive regulation of interleukin-6 biosynthetic processIMP
GO:0046330positive regulation of JNK cascadeIMP
GO:0050830defense response to Gram-positive bacteriumISS
GO:0051092positive regulation of NF-kappaB transcription factor activityIMP
GO:0070374positive regulation of ERK1 and ERK2 cascadeIMP
GO:00709353'-UTR-mediated mRNA stabilizationIDA
GO:0071221cellular response to bacterial lipopeptideISS
GO:0071223cellular response to lipoteichoic acidISS
GO:0090023positive regulation of neutrophil chemotaxisISS
GO:0090073positive regulation of protein homodimerization activityIDA
GO:2000340positive regulation of chemokine (C-X-C motif) ligand 1 productionISS
GO:2000343positive regulation of chemokine (C-X-C motif) ligand 2 productionISS
cellular_component
GO:0005737cytoplasmIEA
GO:0005886plasma membraneTAS
GO:0030139endocytic vesicleISS
GO:0031224intrinsic to membraneIEA
GO:0032587ruffle membraneISS
molecular_function
GO:0004888transmembrane signaling receptor activityIEA
GO:0005515protein bindingIPI
GO:0005546phosphatidylinositol-4,5-bisphosphate bindingISS
GO:0030674protein binding, bridgingNAS
GO:0035662Toll-like receptor 4 bindingIPI
GO:0035663Toll-like receptor 2 bindingIPI
GO:0042803protein homodimerization activityISS
GO:0046982protein heterodimerization activityIDA
GO:0072568protein kinase C delta bindingIPI

Protein-protein interaction details for TIRAP (Homo sapiens)
(Information is obtained from BioGRID)
Not available