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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for TIRAP (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0002224
toll-like receptor signaling pathway
TAS
GO:0002755
MyD88-dependent toll-like receptor signaling pathway
TAS
GO:0006954
inflammatory response
IEA
GO:0007165
signal transduction
IEA
GO:0007166
cell surface receptor linked signaling pathway
ISS
GO:0008063
Toll signaling pathway
TAS
GO:0030099
myeloid cell differentiation
ISS
GO:0030890
positive regulation of B cell proliferation
ISS
GO:0032496
response to lipopolysaccharide
IDA
GO:0032648
regulation of interferon-beta production
ISS
GO:0032735
positive regulation of interleukin-12 production
ISS
GO:0032738
positive regulation of interleukin-15 production
IDA
GO:0032757
positive regulation of interleukin-8 production
IMP
GO:0032760
positive regulation of tumor necrosis factor production
IMP
GO:0034130
toll-like receptor 1 signaling pathway
TAS
GO:0034134
toll-like receptor 2 signaling pathway
TAS
GO:0034137
positive regulation of toll-like receptor 2 signaling pathway
IMP
GO:0034141
positive regulation of toll-like receptor 3 signaling pathway
ISS
GO:0034142
toll-like receptor 4 signaling pathway
TAS
GO:0034145
positive regulation of toll-like receptor 4 signaling pathway
IMP
GO:0035665
TIRAP-dependent toll-like receptor 4 signaling pathway
IDA
GO:0043123
positive regulation of I-kappaB kinase/NF-kappaB cascade
IMP
GO:0044130
negative regulation of growth of symbiont in host
ISS
GO:0045087
innate immune response
IEA
GO:0045087
innate immune response
TAS
GO:0045088
regulation of innate immune response
IC
GO:0045410
positive regulation of interleukin-6 biosynthetic process
IMP
GO:0046330
positive regulation of JNK cascade
IMP
GO:0050830
defense response to Gram-positive bacterium
ISS
GO:0051092
positive regulation of NF-kappaB transcription factor activity
IMP
GO:0070374
positive regulation of ERK1 and ERK2 cascade
IMP
GO:0070935
3'-UTR-mediated mRNA stabilization
IDA
GO:0071221
cellular response to bacterial lipopeptide
ISS
GO:0071223
cellular response to lipoteichoic acid
ISS
GO:0090023
positive regulation of neutrophil chemotaxis
ISS
GO:0090073
positive regulation of protein homodimerization activity
IDA
GO:2000340
positive regulation of chemokine (C-X-C motif) ligand 1 production
ISS
GO:2000343
positive regulation of chemokine (C-X-C motif) ligand 2 production
ISS
cellular_component
GO:0005737
cytoplasm
IEA
GO:0005886
plasma membrane
TAS
GO:0030139
endocytic vesicle
ISS
GO:0031224
intrinsic to membrane
IEA
GO:0032587
ruffle membrane
ISS
molecular_function
GO:0004888
transmembrane signaling receptor activity
IEA
GO:0005515
protein binding
IPI
GO:0005546
phosphatidylinositol-4,5-bisphosphate binding
ISS
GO:0030674
protein binding, bridging
NAS
GO:0035662
Toll-like receptor 4 binding
IPI
GO:0035663
Toll-like receptor 2 binding
IPI
GO:0042803
protein homodimerization activity
ISS
GO:0046982
protein heterodimerization activity
IDA
GO:0072568
protein kinase C delta binding
IPI
Protein-protein interaction details for TIRAP (
Homo sapiens
)
(Information is obtained from BioGRID)
Not available