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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CDKN2A (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000075 cell cycle checkpoint IMP GO:0000080 G1 phase of mitotic cell cycle TAS GO:0000082 G1/S transition of mitotic cell cycle IDA GO:0000209 protein polyubiquitination IDA GO:0000278 mitotic cell cycle TAS GO:0001953 negative regulation of cell-matrix adhesion IMP GO:0006309 DNA fragmentation involved in apoptotic nuclear change IMP GO:0006364 rRNA processing IEA GO:0006469 negative regulation of protein kinase activity IMP GO:0006917 induction of apoptosis IDA GO:0006917 induction of apoptosis IMP GO:0006919 activation of caspase activity IMP GO:0007049 cell cycle IEA GO:0007050 cell cycle arrest IDA GO:0007050 cell cycle arrest IMP GO:0007265 Ras protein signal transduction IEP GO:0007569 cell aging IEA GO:0008285 negative regulation of cell proliferation IDA GO:0008285 negative regulation of cell proliferation IMP GO:0008544 epidermis development IEA GO:0008637 apoptotic mitochondrial changes IMP GO:0009303 rRNA transcription IEA GO:0010389 regulation of G2/M transition of mitotic cell cycle IMP GO:0030308 negative regulation of cell growth IDA GO:0030889 negative regulation of B cell proliferation ISS GO:0031647 regulation of protein stability ISS GO:0031648 protein destabilization IDA GO:0032088 negative regulation of NF-kappaB transcription factor activity IDA GO:0033088 negative regulation of immature T cell proliferation in thymus ISS GO:0033235 positive regulation of protein sumoylation IMP GO:0033600 negative regulation of mammary gland epithelial cell proliferation IEA GO:0034393 positive regulation of smooth muscle cell apoptosis ISS GO:0035986 senescence-associated heterochromatin focus formation IMP GO:0042326 negative regulation of phosphorylation IDA GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator IDA GO:0045736 negative regulation of cyclin-dependent protein kinase activity IDA GO:0045892 negative regulation of transcription, DNA-dependent IMP GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0046822 regulation of nucleocytoplasmic transport IEA GO:0046825 regulation of protein export from nucleus IMP GO:0048103 somatic stem cell division ISS GO:0050821 protein stabilization IDA GO:0051444 negative regulation of ubiquitin-protein ligase activity ISS GO:0060058 positive regulation of apoptosis involved in mammary gland involution IEA GO:0070534 protein K63-linked ubiquitination IDA GO:0071158 positive regulation of cell cycle arrest IDA GO:0090398 cellular senescence IMP GO:0090399 replicative senescence IMP GO:2000111 positive regulation of macrophage apoptosis ISS GO:2000774 positive regulation of cellular senescence IMP cellular_component GO:0005634 nucleus IDA GO:0005654 nucleoplasm IDA GO:0005654 nucleoplasm IEA GO:0005730 nucleolus IDA GO:0005730 nucleolus IEA GO:0005737 cytoplasm IDA GO:0005829 cytosol TAS GO:0016604 nuclear body IDA GO:0035985 senescence-associated heterochromatin focus IDA GO:0043234 protein complex IDA molecular_function GO:0002039 p53 binding IPI GO:0003677 DNA binding IEA GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0004861 cyclin-dependent protein kinase inhibitor activity IDA GO:0005515 protein binding IPI GO:0008134 transcription factor binding IPI GO:0016301 kinase activity IEA GO:0019901 protein kinase binding IPI GO:0051059 NF-kappaB binding IDA GO:0055105 ubiquitin-protein ligase inhibitor activity ISS GO:0070215 MDM2 binding IPI

Protein-protein interaction details for CDKN2A (Homo sapiens) (Information is obtained from BioGRID)

Not available