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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Pcsk9 (Mus musculus) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001920 negative regulation of receptor recycling ISO GO:0002092 positive regulation of receptor internalization ISO GO:0006508 proteolysis IBA GO:0006629 lipid metabolic process IEA GO:0006641 triglyceride metabolic process IDA GO:0006644 phospholipid metabolic process IDA GO:0006917 induction of apoptosis ISO GO:0007041 lysosomal transport ISO GO:0008202 steroid metabolic process IEA GO:0008203 cholesterol metabolic process IDA GO:0009267 cellular response to starvation IDA GO:0009267 cellular response to starvation ISO GO:0010469 regulation of receptor activity ISO GO:0010989 negative regulation of low-density lipoprotein particle clearance ISO GO:0016485 protein processing ISO GO:0016540 protein autoprocessing ISO GO:0016540 protein autoprocessing ISS GO:0030182 neuron differentiation IDA GO:0030182 neuron differentiation IMP GO:0032799 low-density lipoprotein receptor particle metabolic process IDA GO:0032802 low-density lipoprotein particle receptor catabolic process ISO GO:0032802 low-density lipoprotein particle receptor catabolic process ISS GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process IMP GO:0032869 cellular response to insulin stimulus IDA GO:0032869 cellular response to insulin stimulus ISO GO:0042157 lipoprotein metabolic process IDA GO:0042632 cholesterol homeostasis ISO GO:0042632 cholesterol homeostasis ISS GO:0043086 negative regulation of catalytic activity IEA GO:0043525 positive regulation of neuron apoptosis ISO GO:0043525 positive regulation of neuron apoptosis ISS cellular_component GO:0005576 extracellular region IDA GO:0005615 extracellular space IBA GO:0005615 extracellular space IDA GO:0005615 extracellular space ISO GO:0005764 lysosome ISO GO:0005770 late endosome ISO GO:0005791 rough endoplasmic reticulum ISO GO:0048471 perinuclear region of cytoplasm ISO molecular_function GO:0004252 serine-type endopeptidase activity IBA GO:0004252 serine-type endopeptidase activity ISO GO:0004252 serine-type endopeptidase activity ISS GO:0008233 peptidase activity IEA GO:0008236 serine-type peptidase activity IEA GO:0016787 hydrolase activity IEA GO:0034190 apolipoprotein receptor binding ISO GO:0042802 identical protein binding IEA GO:0050750 low-density lipoprotein particle receptor binding IDA GO:0050750 low-density lipoprotein particle receptor binding ISO GO:0070326 very-low-density lipoprotein particle receptor binding ISO

Protein-protein interaction details for Pcsk9 (Mus musculus) (Information is obtained from BioGRID)

Not available